On the interpretation of the atmospheric mechanism transporting the environmental trigger of Kawasaki Disease.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2019
2019
Historique:
received:
19
03
2019
accepted:
05
11
2019
entrez:
17
12
2019
pubmed:
17
12
2019
medline:
17
4
2020
Statut:
epublish
Résumé
Recent advances on the environmental determinants of Kawasaki Disease have pointed to the important role of the atmospheric transport of a still unknown agent potentially triggering the disease. The hypothesis arose from an innovative methodology combining expertise in climate dynamics, the analysis of ocean and atmosphere data, the use of dispersion models and the search for biological agents in air samples. The approach offered a new perspective to reveal the identity of the potential trigger, but at the same time, it increased the level of complexity, which could potentially lead to the misinterpretation of the mechanisms. Some years after it was originally formulated, we here provide a brief clarification on the approach and limits of the methodology in order to prevent an eventual misuse of our research ideas and theory, so that further research can better focus on the knowledge gaps that still remain open.
Identifiants
pubmed: 31841545
doi: 10.1371/journal.pone.0226402
pii: PONE-D-19-07900
pmc: PMC6913965
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0226402Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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