A Decade of Antifungal Leads from Natural Products: 2010-2019.
antifungal agents
fungal pathogens
natural products
Journal
Pharmaceuticals (Basel, Switzerland)
ISSN: 1424-8247
Titre abrégé: Pharmaceuticals (Basel)
Pays: Switzerland
ID NLM: 101238453
Informations de publication
Date de publication:
12 Dec 2019
12 Dec 2019
Historique:
received:
29
11
2019
revised:
09
12
2019
accepted:
10
12
2019
entrez:
18
12
2019
pubmed:
18
12
2019
medline:
18
12
2019
Statut:
epublish
Résumé
In this review, we discuss novel natural products discovered within the last decade that are reported to have antifungal activity against pathogenic species. Nearly a hundred natural products were identified that originate from bacteria, algae, fungi, sponges, and plants. Fungi were the most prolific source of antifungal compounds discovered during the period of review. The structural diversity of these antifungal leads encompasses all the major classes of natural products including polyketides, shikimate metabolites, terpenoids, alkaloids, and peptides.
Identifiants
pubmed: 31842280
pii: ph12040182
doi: 10.3390/ph12040182
pmc: PMC6958371
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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