The Genetic Architecture of Gliomagenesis-Genetic Risk Variants Linked to Specific Molecular Subtypes.

1p/19q co-deletion IDH mutant etiopathogenesis genotype phenotype glioma gliomagenesis

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
12 Dec 2019
Historique:
received: 28 10 2019
revised: 05 12 2019
accepted: 07 12 2019
entrez: 18 12 2019
pubmed: 18 12 2019
medline: 18 12 2019
Statut: epublish

Résumé

Genome-wide association studies have identified 25 germline genetic loci that increase the risk of glioma. The somatic tumor molecular alterations, including

Identifiants

pubmed: 31842352
pii: cancers11122001
doi: 10.3390/cancers11122001
pmc: PMC6966482
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : NCI NIH HHS
ID : R01CA139020/CA/NCI
Pays : United States
Organisme : Swedish Research Council
ID : 2016-01159_3
Organisme : Swedish Cancer Foundation
ID : CAN 2018/390
Organisme : Northern Sweden Research Foundation
ID : AMP 16-805
Organisme : Umeå University Hospital Grant
ID : BAS-ALF: 7002485
Organisme : Umeå University Hospital Grant
ID : Central-ALF: 7002994

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Auteurs

Wendy Yi-Ying Wu (WY)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Gunnar Johansson (G)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Carl Wibom (C)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Thomas Brännström (T)

Department of Medical Bioscience, Umeå University, 901 87 Umeå, Sweden.

Annika Malmström (A)

Department of Advanced Home Care, Linköping University and Department of Clinical and Experimental Medicine, Linköping University, 581 83 Linköping, Sweden.

Roger Henriksson (R)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Irina Golovleva (I)

Department of Medical Bioscience, Umeå University, 901 87 Umeå, Sweden.

Melissa L Bondy (ML)

Department of Health Research and Policy (Epidemiology), Stanford University School of Medicine, Stanford, CA 94305, USA.
Department of Medicine, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.

Ulrika Andersson (U)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Anna M Dahlin (AM)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Beatrice Melin (B)

Department of Radiation Sciences, Oncology, Umeå University, 901 87 Umeå, Sweden.

Classifications MeSH