Controlled saturation magnetization transfer for reproducible multivendor variable flip angle T
CSMT
DESPOT
JSR
T1 mapping
T2 mapping
magnetization transfer
relaxometry
reproducibility
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
received:
26
07
2019
revised:
15
10
2019
accepted:
14
11
2019
pubmed:
18
12
2019
medline:
15
5
2021
entrez:
18
12
2019
Statut:
ppublish
Résumé
The widespread clinical application of quantitative MRI has been hindered by a lack of reproducibility across sites and vendors. Previous work has attributed this to incorrect B Three healthy volunteers were scanned on scanners from 3 vendors (GE Healthcare, Philips, Siemens). An extensive set of images necessary for joint T Harmonized RF spoiling conditions are insufficient to ensure good cross-vendor reproducibility. Controlled saturation magnetization transfer allows cross-protocol variability to be reduced from 18.3% to 4.0%. Whole-brain variability using the same protocol was reduced from a maximum of 19% to 4.5% across sites. Both CSMT and native vendor RF conditions have a reported variability of less than 5% for repeat measures on the same vendor. Magnetization transfer effects are a major contributor to intersite/intrasite variability of T
Identifiants
pubmed: 31846122
doi: 10.1002/mrm.28109
pmc: PMC7154666
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
221-236Subventions
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Department of Health
Pays : United Kingdom
Organisme : Wellcome Trust
ID : WT 203148/Z/16/Z
Pays : United Kingdom
Informations de copyright
© 2019 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.
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