Utilizing
Journal
The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R
Informations de publication
Date de publication:
17 01 2020
17 01 2020
Historique:
pubmed:
18
12
2019
medline:
18
12
2019
entrez:
18
12
2019
Statut:
ppublish
Résumé
Lead time and cost are important factors for any pharmaceutical API. However, these issues become even more important when the drug substance contains an isotope such as deuterium, which has a natural abundance of only ∼0.016% of all hydrogen. Fewer suppliers and logistical barriers both play a role in driving up the cost. These factors can challenge the supply route used to manufacture
Identifiants
pubmed: 31846324
doi: 10.1021/acs.joc.9b02552
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM