Adult Measles - Case Reports of a Highly Contagious Disease.
Encephalopathy
Maculopapular rash
Measles
Pneumonia
Thrombocytopenia
Vaccination
Viral exanthema
Journal
Open access Macedonian journal of medical sciences
ISSN: 1857-9655
Titre abrégé: Open Access Maced J Med Sci
Pays: North Macedonia
ID NLM: 101662294
Informations de publication
Date de publication:
30 Sep 2019
30 Sep 2019
Historique:
received:
07
04
2019
revised:
04
05
2019
accepted:
05
06
2019
entrez:
19
12
2019
pubmed:
19
12
2019
medline:
19
12
2019
Statut:
epublish
Résumé
Measles is highly contagious and is caused by the RNA morbillivirus. The best protection is active immunisation in early childhood. Without immunisation morbidity and mortality of measles are high. In recent years, an increasing number of adult measles has been recognised in Europe. We report here on two adult patients - a 40-year-old male and a 55-year-old female - who presented with fever, fatigue, cough, coryza, conjunctivitis and maculopapular rash. The suspicion of adult measles infection was confirmed by positivity for IgM antibodies against measles virus and reverse-transcriptase polymerase chain reaction in blood and urine. Patients were isolated, and the treatment was symptomatic. In the younger patient, complete recovery was achieved within two weeks. In the older patient, an acute encephalopathy developed after initial improvement characterised by cognitive impairment. In patients presenting with fever and maculopapular rash and fatigue, measles should be considered even in adult patients. Early diagnosis with subsequent isolation and registration of patients are important measures to prevent local outbreaks of the disease.
Sections du résumé
BACKGROUND
BACKGROUND
Measles is highly contagious and is caused by the RNA morbillivirus. The best protection is active immunisation in early childhood. Without immunisation morbidity and mortality of measles are high. In recent years, an increasing number of adult measles has been recognised in Europe.
CASE REPORTS
METHODS
We report here on two adult patients - a 40-year-old male and a 55-year-old female - who presented with fever, fatigue, cough, coryza, conjunctivitis and maculopapular rash. The suspicion of adult measles infection was confirmed by positivity for IgM antibodies against measles virus and reverse-transcriptase polymerase chain reaction in blood and urine. Patients were isolated, and the treatment was symptomatic. In the younger patient, complete recovery was achieved within two weeks. In the older patient, an acute encephalopathy developed after initial improvement characterised by cognitive impairment.
CONCLUSIONS
CONCLUSIONS
In patients presenting with fever and maculopapular rash and fatigue, measles should be considered even in adult patients. Early diagnosis with subsequent isolation and registration of patients are important measures to prevent local outbreaks of the disease.
Identifiants
pubmed: 31850111
doi: 10.3889/oamjms.2019.540
pii: OAMJMS-7-3009
pmc: PMC6910791
doi:
Types de publication
Case Reports
Langues
eng
Pagination
3009-3012Informations de copyright
Copyright: © 2019 André Koch, Claudia Krönert, Torello Lotti, Aleksandra Vojvodic, Uwe Wollina.
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