Printing bone in a gel: using nanocomposite bioink to print functionalised bone scaffolds.
Biofabrication
Bioinks
Gellan
Growth factor delivery
Laponite®
Skeletal tissue
Journal
Materials today. Bio
ISSN: 2590-0064
Titre abrégé: Mater Today Bio
Pays: England
ID NLM: 101757228
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
22
06
2019
revised:
05
09
2019
accepted:
06
09
2019
entrez:
20
12
2019
pubmed:
20
12
2019
medline:
20
12
2019
Statut:
ppublish
Résumé
Free-form printing offers a novel biofabrication approach to generate complex shapes by depositing hydrogel materials within a temporary supportive environment. However, printed hydrogels typically lack the requisite mechanical properties and functionality of the desired tissue, limiting application and, more importantly, safety and efficacy of the implant. The study authors have developed an innovative nanoclay-based bioink to print high shape fidelity functional constructs for potential skeletal application. Laponite® (LAP) nanoclay was combined with gellan gum (GG) to generate a printable hydrogel that was highly stable
Identifiants
pubmed: 31853520
doi: 10.1016/j.mtbio.2019.100028
pii: S2590-0064(19)30054-7
pii: 100028
pmc: PMC6894340
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100028Subventions
Organisme : Medical Research Council
ID : MR/L012626/1
Pays : United Kingdom
Informations de copyright
© 2019 The Authors.
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