Ebola Virus Disease Outbreak - Democratic Republic of the Congo, August 2018-November 2019.


Journal

MMWR. Morbidity and mortality weekly report
ISSN: 1545-861X
Titre abrégé: MMWR Morb Mortal Wkly Rep
Pays: United States
ID NLM: 7802429

Informations de publication

Date de publication:
20 Dec 2019
Historique:
entrez: 20 12 2019
pubmed: 20 12 2019
medline: 21 12 2019
Statut: epublish

Résumé

On August 1, 2018, the Democratic Republic of the Congo Ministry of Health (DRC MoH) declared the tenth outbreak of Ebola virus disease (Ebola) in DRC, in the North Kivu province in eastern DRC on the border with Uganda, 8 days after another Ebola outbreak was declared over in northwest Équateur province. During mid- to late-July 2018, a cluster of 26 cases of acute hemorrhagic fever, including 20 deaths, was reported in North Kivu province.* Blood specimens from six patients hospitalized in the Mabalako health zone and sent to the Institut National de Recherche Biomédicale (National Biomedical Research Institute) in Kinshasa tested positive for Ebola virus. Genetic sequencing confirmed that the outbreaks in North Kivu and Équateur provinces were unrelated. From North Kivu province, the outbreak spread north to Ituri province, and south to South Kivu province (1). On July 17, 2019, the World Health Organization designated the North Kivu and Ituri outbreak a public health emergency of international concern, based on the geographic spread of the disease to Goma, the capital of North Kivu province, and to Uganda and the challenges to implementing prevention and control measures specific to this region (2). This report describes the outbreak in the North Kivu and Ituri provinces. As of November 17, 2019, a total of 3,296 Ebola cases and 2,196 (67%) deaths were reported, making this the second largest documented outbreak after the 2014-2016 epidemic in West Africa, which resulted in 28,600 cases and 11,325 deaths.

Identifiants

pubmed: 31856146
doi: 10.15585/mmwr.mm6850a3
pmc: PMC6936163
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1162-1165

Investigateurs

Walter Alarcon (W)
Jesse Bonwitt (J)
Dante Bugli (D)
Nirma D Bustamante (ND)
Mary Choi (M)
Benjamin A Dahl (BA)
Kevin DeCock (K)
Amber Dismer (A)
Reena Doshi (R)
Christine Dubray (C)
David Fitter (D)
Margherita Ghiselli (M)
Noemi Hall (N)
Amen Ben Hamida (A)
Andrea M McCollum (AM)
John Neatherlin (J)
Pratima L Raghunathan (PL)
Fatima Ravat (F)
Mary G Reynolds (MG)
Adriana Rico (A)
Nailah Smith (N)
Gnakub Norbert Soke (GN)
Aimee T Trudeau (AT)
Kerton R Victory (KR)
Mary Claire Worrell (MC)

Déclaration de conflit d'intérêts

All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

Références

MMWR Morb Mortal Wkly Rep. 2015 Jan 16;64(1):20-7
pubmed: 25590682
Lancet. 2018 Oct 13;392(10155):1295-1296
pubmed: 30322568
N Engl J Med. 2019 Dec 12;381(24):2293-2303
pubmed: 31774950
MMWR Morb Mortal Wkly Rep. 2015 Apr 17;64(14):386-8
pubmed: 25879897
N Engl J Med. 2014 Nov 27;371(22):2083-91
pubmed: 25317743
J Infect Dis. 2017 Jul 1;216(suppl_1):S368-S372
pubmed: 28838202
N Engl J Med. 2017 Jan 26;376(4):330-341
pubmed: 25830322
N Engl J Med. 2019 Jul 25;381(4):373-383
pubmed: 31141654
J Allergy Clin Immunol. 2015 Apr;135(4):856-67
pubmed: 25843598

Auteurs

Aaron Aruna (A)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Placide Mbala (P)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Luigi Minikulu (L)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Daniel Mukadi (D)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Dorothée Bulemfu (D)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Franck Edidi (F)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Junior Bulabula (J)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Gaston Tshapenda (G)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Justus Nsio (J)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Richard Kitenge (R)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Gisèle Mbuyi (G)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Celestin Mwanzembe (C)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

John Kombe (J)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Léopold Lubula (L)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Jean Christophe Shako (JC)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Mathias Mossoko (M)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Felix Mulangu (F)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Annie Mutombo (A)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Emilia Sana (E)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Yannick Tutu (Y)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Laetycia Kabange (L)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Jonathan Makengo (J)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Fortunat Tshibinkufua (F)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Steve Ahuka-Mundeke (S)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

Jean-Jacques Muyembe (JJ)

Ministry of Health, Kinshasa, Democratic Republic of the Congo.

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