Tritiated Water Exposure in Zebrafish (Danio rerio): Effects on the Early-Life Stages.
Animals
Biomarkers
/ metabolism
Dose-Response Relationship, Drug
Embryo, Nonmammalian
/ drug effects
Embryonic Development
/ drug effects
Gene Expression
/ drug effects
Larva
/ drug effects
Random Allocation
Tritium
/ toxicity
Water Pollutants, Radioactive
/ toxicity
Zebrafish
/ growth & development
Biomarkers
DNA damage
Reactive oxygen species production
Tritiated water
Zebrafish embryo-larvae
Journal
Environmental toxicology and chemistry
ISSN: 1552-8618
Titre abrégé: Environ Toxicol Chem
Pays: United States
ID NLM: 8308958
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
28
10
2019
revised:
15
11
2019
accepted:
14
12
2019
pubmed:
21
12
2019
medline:
5
11
2020
entrez:
21
12
2019
Statut:
ppublish
Résumé
Tritium, a radioactive isotope of hydrogen of natural and anthropogenic origin, is ubiquitously present in the environment. Effluents of nuclear centers of production are significant anthropogenic sources. With the upcoming project of thermonuclear fusion, tritium releases in the environment may increase. It is therefore important to characterize the ecological risk linked to tritium. The effects of tritiated water (HTO) were therefore studied in zebrafish larvae exposed for 10 d to different dose rates, 1.1 × 10
Substances chimiques
Biomarkers
0
Water Pollutants, Radioactive
0
Tritium
10028-17-8
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
648-658Subventions
Organisme : GGP environnement
Pays : International
Informations de copyright
© 2019 SETAC.
Références
Adam-Guillermin C, Pereira S, Cavalié I, Orjollet D. 2013. Sensibilité, spécificité et représentativité potentielle de marqueurs de génotoxicité pour l'analyse des effets des radionucléides. Application au tritium et à l'irradiation gamma (action GGP-Environnement, fiche V1-201, année 2012). Rapport IRSN/PRP-ENV/SERIS/2013-005. Institut de Radioprotection et de Sûreté Nucléaire, Cadarache, France.
Adam-Guillermin C, Pereira S, Della-Vedova C, Hinton T, Garnier-Laplace J. 2012. Genotoxic and reprotoxic effects of tritium and external gamma irradiation on aquatic animals. Rev Environ Contam Toxicol 220:67-103.
Arcanjo C, Armant O, Floriani M, Cavalie I, Camilleri V, Simon O, Orjollet D, Adam-Guillermin C, Gagnaire B. 2018. Tritiated water exposure disrupts myofibril structure and induces mis-regulation of eye opacity and DNA repair genes in zebrafish early life stages. Aquat Toxicol 200:114-126.
Arcanjo C, Maro D, Camilleri V, Cavalié I, Simon O, Beaugelin-Seiller K, Carasco L, Orjollet D, Adam-Guillermin C, Gagnaire B. 2019. Assessing tritium internalisation in zebrafish early life stages: Importance of rapid isotopic exchange. J Environ Radioact 203:30-38.
Autorité de Sûreté Nucléaire. 2010. Livre blanc du tritium. Montrouge, France. [cited 2019 September 3]. Available from: http://www.asn.fr/sites/tritium
Bannister L, Serran M, Bertrand L, Klokov D, Wyatt H, Blimkie M, Gueguen Y, Priest N, Jourdain JR, Sykes P. 2016. Environmentally relevant chronic low-dose tritium and gamma exposures do not increase somatic intrachromosomal recombination in pKZ1 mouse spleen. Radiat Res 186:539-548.
Boyer C, Vichot L, Fromm M, Losset Y, Tatin-Froux F, Guétat P, Badot PM. 2009. Tritium in plants: A review of current knowledge. Environ Exp Bot 67:34-51.
Brown JE, Alfonso B, Avila R, Beresford NA, Copplestone D, Pröhl G, Ulanovsky A. 2008. The ERICA tool. J Environ Radioact 99:1371-1383.
Canadian Nuclear Safety Commission. 2008. Standards and guidelines for tritium in drinking water. Ottawa, ON, Canada.
Delbart C. 2000. Les Mitochondries: Biologie et Incidences Physiopathologiques. Tec & Doc, Paris.
Devaux A, Flammarion P, Bernardon V, Garric J, Monod G. 1998. Monitoring of the chemical pollution of the river Rhone through measurement of DNA damage and cytochrome P4501A induction in chub (Leuciscus cephalus). Mar Environ Res 46:257-262.
Erickson RC. 1971. Effects of chronic irradiation by tritiated water on Poecilia reticulata, the guppy, National Technical Information Service, US Department of Commerce, Springfield, VA.
Festarini A, Shultz C, Stuart M, Kim SB, Ferreri C. 2019. Cellular responses in rainbow trout (Oncorhynchus mykiss) reared in tritiated water and/or fed organically bound tritium. Appl Radiat Isot 151:217-225.
Fraysse B, Mons R, Garric J. 2006. Development of a zebrafish 4-day embryo-larval bioassay to assess toxicity of chemicals. Ecotoxicol Environ Saf 63:253-267.
Gagnaire B, Adam-Guillermin C, Festarini A, Cavalié I, Della-Vedova C, Shultz C, Kim SB, Ikert H, Dubois C, Walsh S, Farrow F, Beaton D, Tan E, Wen K, Stuart M. 2017. Effects of in situ exposure to tritiated natural environments: A multi-biomarker approach using the fathead minnow, Pimephales promelas. Sci Total Environ 599-600:597-611.
Gagnaire B, Cavalie I, Camilleri V, Adam-Guillermin C. 2013. Effects of depleted uranium on oxidative stress, detoxification, and defence parameters of zebrafish Danio rerio. Arch Environ Contam Toxicol 64:140-150.
Gagnaire B, Cavalié I, Pereira S, Floriani M, Dubourg N, Camilleri V, Adam-Guillermin C. 2015. External gamma irradiation-induced effects in early-life stages of zebrafish, Danio rerio. Aquat Toxicol 169:69-78.
Gagnaire B, Gosselin I, Festarini A, Walsh S, Cavalié I, Adam-Guillermin C, Della-Vedova C, Farrow F, Kim SB, Shkarupin A, Chen HQ, Beaton D, Stuart M. 2020. Effects of in vivo exposure to tritium: A multi-biomarker approach using the fathead minnow, Pimephales promelas. Environ Sci Pollut Res 27:3612-3623.
Galeriu D, Melintescu A. 2011. A model approach for tritium dynamics in wild mammals. Radioprotection 46(6 Suppl.):S445-S451.
Garnier-Laplace J, Della-Vedova C, Andersson P, Copplestone D, Cailes C, Beresford NA, Howard BJ, Howe P, Whitehouse P. 2010. A multi-criteria weight of evidence approach for deriving ecological benchmarks for radioactive substances. J Radiol Prot 30:215-233.
Garnier-Laplace J, Della-Vedova C, Gilbin R, Copplestone D, Hingston J, Ciffroy P. 2006. First derivation of predicted-no-effect values for freshwater and terrestrial ecosystems exposed to radioactive substances. Environ Sci Technol 40:6498-6505.
Hill AJ, Teraoka H, Heideman W, Peterson RE. 2005. Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci 86:6-19.
Hyodo-Taguchi Y, Etoh H. 1993. Vertebral malformations in medaka (teleost fish) after exposure to tritiated water in the embryonic stage. Radiat Res 135:400-404.
Ichikawa R, Suyama I. 1974. Effects of tritiated water on the embryonic development of two marine teleosts. Bull Jpn Soc Sci Fish 40:819-824.
International Commission on Radiological Protection. 2008. Environmental protection: The concept and use of reference animals and plants. ICRP Publication 108. Annals of the ICRP 38:1-242.
Jaeschke BC, Millward GE, Moody AJ, Jha AN. 2011. Tissue-specific incorporation and genotoxicity of different forms of tritium in the marine mussel, Mytilus edulis. Environ Pollut 159:274-280.
Jha AN, Dogra Y, Turner A, Millward GE. 2005. Impact of low doses of tritium on the marine mussel, Mytilus edulis: Genotoxic effects and tissue-specific bioconcentration. Mutat Res 586:47-57.
Kim SB, Bredlaw M, Rousselle H, Stuart M. 2019. Distribution of organically bound tritium (OBT) activity concentrations in aquatic biota from eastern Canada. J Environ Radioact 208-209:105997.
Kim SB, Korolevych V. 2013. Quantification of exchangeable and non-exchangeable organically bound tritium (OBT) in vegetation. J Environ Radioact 118:9-14.
Kim SB, Shultz C, Stuart M, Festarini A. 2015. Tritium uptake in rainbow trout (Oncorhynchus mykiss): HTO and OBT-spiked feed exposures simultaneously. Appl Radiat Isot 98:96-102.
Mathur-De Vré R, Binet J. 1984. Molecular aspects of tritiated water and natural water in radiation biology. Prog Biophys Mol Biol 43:161-193.
Melintescu A, Galeriu D, Diabaté S, Strack S. 2015. Preparatory steps for a robust dynamic model for organically bound tritium dynamics in agricultural crops. Fusion Science and Technology 67:479-482.
Mothersill C, Seymour C. 2009. Communication of ionising radiation signals a tale of two fish. Int J Radiat Biol 85:909-919.
Oberemm A. 2000. The use of a refined zebrafish embryo bioassay for the assessment of aquatic toxicity. Lab Anim (NY) 29:32-40.
Organisation for Economic Co-operation and Development. 2004a. Test No. 210: Fish, early-life stage toxicity test. OECD Guidelines for Testing of Chemicals. Paris, France.
Organisation for Economic Co-operation and Development. 2004b. Test No. 212: Fish, short-term toxicity test on embryo and sac-fry stages. OECD Guidelines for Testing of Chemicals. Paris, France.
Pereira S, Bourrachot S, Cavalie I, Plaire D, Dutilleul M, Gilbin R, Adam-Guillermin C. 2011. Genotoxicity of acute and chronic gamma-irradiation on zebrafish cells and consequences for embryo development. Environ Toxicol Chem 30:2831-2837.
Pfaffl MW, Horgan GW, Dempfle L. 2002. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36.
R Development Core Team. 2004. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria.
Sato M, Kondoh M. 2002. Recent studies on metallothionein: Protection against toxicity of heavy metals and oxygen free radicals. Tohoku J Exp Med 196:9-22.
Sazykina TG, Kryshev AI. 2003. EPIC database on the effects of chronic radiation in fish: Russian/FSU data. J Environ Radioact 68:65-87.
Scholz S, Fischer S, Gündel U, Küster E, Luckenbach T, Voelker D. 2008. The zebrafish embryo model in environmental risk assessment-Applications beyond acute toxicity testing. Environ Sci Pollut Res 15:394-404.
Simon O, Massarin S, Coppin F, Hinton TG, Gilbin R. 2011. Investigating the embryo/larval toxic and genotoxic effects of Î3 irradiation on zebrafish eggs. J Environ Radioact 102:1039-1044.
Strand JA, Fujihara MP, Poston TM, Abernethy CS. 1982. Permanence of suppression of the primary immune response in rainbow trout, Salmo gairdneri, sublethally exposed to tritiated water during embryogenesis. Radiat Res 91:533-541.
Stuart M, Festarini A, Schleicher K, Tan E, Kim SB, Wen K, Gawlik J, Ulsh B. 2016. Biological effects of tritium on fish cells in the concentration range of international drinking water standards. Int J Radiat Biol 92:563-571.
Suyama I, Etoh H, Maruyama T, Kato Y, Ichikawa R. 1981. Effects of ionizing radiation on the early development of Oryzias eggs. J Radiat Res 22:125-133.
van der Oost R, Beyer J, Vermeulen NPE. 2003. Fish bioaccumulation and biomarkers in environmental risk assessment: A review. Environ Toxicol Pharmacol 13:57-149.
Walden SJ. 1971. Effects of tritiated water on the embryonic development of the three-spine stickleback, Gasterosteus aculeatus Linnaeus. In Nelson DJ, ed, Radionuclides in Ecosystems. National Technical Information Service. US Department of commerce, Springfield, VA, pp. 1087-1097.
Westerfield M. 2007. The Zebrafish Book: A Guide for the Laboratory Use of Zebrafish (Danio rerio), University of Oregon, Eugene, OR, USA.