Biotechnological potential and applications of microbial consortia.
Consolidated bioprocessing
Environment bio-remediation
Human health supervision
Microbial consortia application
Microbial consortia construction challenges
Valuable compounds synthesis
Journal
Biotechnology advances
ISSN: 1873-1899
Titre abrégé: Biotechnol Adv
Pays: England
ID NLM: 8403708
Informations de publication
Date de publication:
Historique:
received:
09
05
2019
revised:
13
11
2019
accepted:
17
12
2019
pubmed:
22
12
2019
medline:
7
5
2020
entrez:
22
12
2019
Statut:
ppublish
Résumé
Recent advances in microbial consortia present a valuable approach for expanding the scope of metabolic engineering. Systems biology enable thorough understanding of diverse physiological processes of cells and their interactions, which in turn offers insights into the optimal design of synthetic microbial consortia. Yet, the study of synthetic microbial consortia is still in early infancy, facing many unknowns and challenges in intercellular communication and construction of stable and controllable microbial consortia systems. In this review, we comprehensively discussed the recent application of defined microbial consortia in the fields of human health monitoring and medicine exploitation, valuable compounds synthesis, consolidated bioprocessing of lignocellulosic materials and environmental bioremediation. Moreover, the outstanding challenges and future directions to advance the development of high-efficient, stable and controllable synthetic microbial consortia were highlighted.
Identifiants
pubmed: 31862233
pii: S0734-9750(19)30200-9
doi: 10.1016/j.biotechadv.2019.107500
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
107500Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.