Normative data for multiple breath washout outcomes in school-aged Caucasian children.


Journal

The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460

Informations de publication

Date de publication:
04 2020
Historique:
received: 02 07 2019
accepted: 10 12 2019
pubmed: 22 12 2019
medline: 22 6 2021
entrez: 22 12 2019
Statut: epublish

Résumé

The multiple breath nitrogen washout (N N Analysis used 485 trials from 180 healthy Caucasian children aged from 6 to 18 years old. While LCI increased with age, this increase was negligible (0.04 units·year We report reference values for N

Sections du résumé

BACKGROUND
The multiple breath nitrogen washout (N
METHODS
N
RESULTS
Analysis used 485 trials from 180 healthy Caucasian children aged from 6 to 18 years old. While LCI increased with age, this increase was negligible (0.04 units·year
CONCLUSION
We report reference values for N

Identifiants

pubmed: 31862765
pii: 13993003.01302-2019
doi: 10.1183/13993003.01302-2019
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentIn
Type : ErratumIn

Informations de copyright

Copyright ©ERS 2020.

Déclaration de conflit d'intérêts

Conflict of interest: P. Anagnostopoulou has nothing to disclose. Conflict of interest: P. Latzin reports personal fees from Gilead, Novartis, Polyphor, Santhera, Schwabe, Vertex, Vifor and Zambon, as well as grants from Vertex, outside the submitted work. Conflict of interest: R. Jensen has nothing to disclose. Conflict of interest: M. Stahl reports personal fees from Vertex Pharmaceuticals, outside the submitted work. Conflict of interest: A. Harper has nothing to disclose. Conflict of interest: S. Yammine has nothing to disclose. Conflict of interest: J. Usemann has nothing to disclose. Conflict of interest: R.E. Foong has nothing to disclose. Conflict of interest: B. Spycher has nothing to disclose. Conflict of interest: G.L. Hall reports grants from the NHMRC and the Australia and USA CF Foundation, and non-financial support (loan of equipment) from ndd, during the conduct of the study. Conflict of interest: F. Singer reports personal fees from Vertex and Novartis, outside the submitted work. Conflict of interest: S. Stanojevic has nothing to disclose. Conflict of interest: M.A. Mall reports grants from the German Federal Ministry of Education and Research (82DZL004A1) and the Einstein Foundation Berlin (EP-2017-393), during the conduct of the study, and personal fees advisory board work, consultancy and lectures from Boehringer Ingelheim and Vertex Pharmaceuticals, outside the submitted work. Conflict of interest: F. Ratjen reports grants and personal fees for consultancy from Vertex, plus personal fees for consultancy from Novartis, Bayer, Roche and Genetech, outside the submitted work. Conflict of interest: K.A. Ramsey has nothing to disclose.

Auteurs

Pinelopi Anagnostopoulou (P)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.
Insitute of Anatomy, University of Bern, Bern, Switzerland.
Medical School, University of Cyprus, Nicosia, Cyprus (current affiliation).

Philipp Latzin (P)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.

Renee Jensen (R)

Division of Respiratory Medicine, The Hospital for Sick Children and Translational Medicine, SickKids Research Institute, University of Toronto, Toronto, ON, Canada.

Mirjam Stahl (M)

Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.
Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Dept of Pediatrics, University of Heidelberg, Heidelberg, Germany.

Alana Harper (A)

Telethon Kids Institute, Perth, Australia.

Sophie Yammine (S)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.

Jakob Usemann (J)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.
University of Basel Children's Hospital (UKBB), Basel, Switzerland.

Rachel E Foong (RE)

Telethon Kids Institute, Perth, Australia.
School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia.

Ben Spycher (B)

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Graham L Hall (GL)

Telethon Kids Institute, Perth, Australia.
School of Physiotherapy and Exercise Science, Curtin University, Perth, Australia.

Florian Singer (F)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.

Sanja Stanojevic (S)

Division of Respiratory Medicine, The Hospital for Sick Children and Translational Medicine, SickKids Research Institute, University of Toronto, Toronto, ON, Canada.

Marcus A Mall (MA)

Dept of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.
Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Dept of Pediatrics, University of Heidelberg, Heidelberg, Germany.
Dept of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Berlin Institute of Health (BIH), Berlin, Germany.

Felix Ratjen (F)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland felix.ratjen@sickkids.ca.
F. Ratjen and K.A. Ramsey contributed equally as last authors.

Kathryn A Ramsey (KA)

Division of Respiratory Medicine, Dept of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.
Telethon Kids Institute, Perth, Australia.
F. Ratjen and K.A. Ramsey contributed equally as last authors.

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