Adverse Drug Reaction Detection in Social Media by Deepm Learning Methods.

Adverse Drug Reaction Classification Deep Learning Natural Language Processing Social Network

Journal

Cell journal
ISSN: 2228-5806
Titre abrégé: Cell J
Pays: Iran
ID NLM: 101566618

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 25 12 2018
accepted: 14 04 2019
entrez: 22 12 2019
pubmed: 22 12 2019
medline: 22 12 2019
Statut: ppublish

Résumé

Health-related studies have been recently at the heart attention of the media. Social media, such as Twitter, has become a valuable online tool to describe the early detection of various adverse drug reactions (ADRs). Different medications have adverse effects on various cells and tissues, sometimes more than one cell population would be adversely affected. These types of side effect are occasionally associated with the direct or indirect influence of prescribed drugs but do not have general unfavorable mutagenic consequences on patients. This study aimed to demonstrate a quick and accurate method to collect and classify information based on the distribution of approved data on Twitter. In this classification method, we selected "ask a patient" dataset and combination of Twitter "Ask a Patient" datasets that comprised of 6,623, 26,934, and 11,623 reviews. We used deep learning methods with the word2vec to classify ADR comments posted by the users and present an architecture by HAN, FastText, and CNN. Natural language processing (NLP) deep learning is able to address more advanced peculiarity in learning information compared to other types of machine learning. Moreover, the current study highlighted the advantage of incorporating various semantic features, including topics and concepts. Our approach predicts drug safety with the accuracy of 93% (the combination of Twitter and "Ask a Patient" datasets) in a binary manner. Despite the apparent benefit of various conventional classifiers, deep learningbased text classification methods seem to be precise and influential tools to detect ADR.

Identifiants

pubmed: 31863657
doi: 10.22074/cellj.2020.6615
pmc: PMC6947008
doi:

Types de publication

Journal Article

Langues

eng

Pagination

319-324

Informations de copyright

Copyright© by Royan Institute. All rights reserved.

Déclaration de conflit d'intérêts

There is no conflict of interest in this study.

Références

JAMA. 1997 Jan 22-29;277(4):301-6
pubmed: 9002492
Ann Pharmacother. 2008 Jul;42(7):1017-25
pubmed: 18594048
J Pharmacol Pharmacother. 2013 Dec;4(Suppl 1):S73-7
pubmed: 24347988
Drug Saf. 2014 Oct;37(10):777-90
pubmed: 25151493
J Biomed Inform. 2015 Feb;53:196-207
pubmed: 25451103

Auteurs

Zahra Rezaei (Z)

Department of Computer and Electrical Engineering, University of Kashan, Kashan, Iran. Electronic Address: z.rezaei2010@gmail.com.

Hossein Ebrahimpour-Komleh (H)

Department of Computer and Electrical Engineering, University of Kashan, Kashan, Iran. Electronic Address: ebrahimpour@kashanu.ac.ir.

Behnaz Eslami (B)

Department of Computer Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Ramyar Chavoshinejad (R)

Mabna Veterinary Lab, Karaj, Alborz, Iran.

Mehdi Totonchi (M)

Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

Classifications MeSH