Management of Renal Cell Carcinoma-Current Practice in Sub-Saharan Africa.
immuotherapy
management
radical nephrectomy
renal cell carcinoma
sub-saharan africa
Journal
Journal of kidney cancer and VHL
ISSN: 2203-5826
Titre abrégé: J Kidney Cancer VHL
Pays: Australia
ID NLM: 101695919
Informations de publication
Date de publication:
2019
2019
Historique:
received:
27
08
2019
accepted:
01
11
2019
entrez:
24
12
2019
pubmed:
24
12
2019
medline:
24
12
2019
Statut:
epublish
Résumé
There is a global variation in the incidence of renal masses with the developed nations having a greater incidence. About 80-90% of renal malignancies are renal cell carcinomas (RCC) which account for 2-4% of all cancers. In Africa and the Middle East, the age-standardized incidence for RCC is 1.8-4.8/100,000 for males and 1.2-2.2/100,000 for females. The management of renal cell cancer is challenging. A multidisciplinary approach is effective for diagnosis, staging, and treatment. Guidelines recommend active surveillance, thermal ablation, partial nephrectomy, radical nephrectomy, cytoreductive nephrectomy and immunotherapy as various modalities for various stages of RCC. However, open radical nephrectomy is most widely adopted as an option for treatment at various stages of the disease in sub-Saharan Africa due to its cost-effectiveness, applicability at various stages, and the reduced cost of follow-up. Nevertheless, most patients in the region present with the disease in the advanced stage and despite surgery the prognosis is poor.
Identifiants
pubmed: 31867157
doi: 10.15586/jkcvhl.2019.122
pii: 122
pmc: PMC6898899
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1-9Informations de copyright
© Cassell A et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest regarding this article.
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