Outdoor Air Pollution and Brain Structure and Function From Across Childhood to Young Adulthood: A Methodological Review of Brain MRI Studies.

air pollution brain development magnetic resonance imaging (MRI) neuroimaging

Journal

Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579

Informations de publication

Date de publication:
2019
Historique:
received: 17 04 2019
accepted: 25 10 2019
entrez: 24 12 2019
pubmed: 24 12 2019
medline: 24 12 2019
Statut: epublish

Résumé

Outdoor air pollution has been recognized as a novel environmental neurotoxin. Studies have begun to use brain Magnetic Resonance Imaging (MRI) to investigate how air pollution may adversely impact developing brains. A systematic review was conducted to evaluate and synthesize the reported evidence from MRI studies on how early-life exposure to outdoor air pollution affects neurodevelopment. Using PubMed and Web of Knowledge, we conducted a systematic search, followed by structural review of original articles with individual-level exposure data and that met other inclusion criteria. Six studies were identified, each sampled from 3 cohorts of children in Spain, The Netherlands, and the United States. All studies included a one-time assessment of brain MRI when children were 6-12 years old. Air pollutants from traffic and/or regional sources, including polycyclic aromatic hydrocarbons (PAHs), nitrogen dioxide, elemental carbon, particulate matter (<2.5 or <10 μm), and copper, were estimated prenatally (

Identifiants

pubmed: 31867298
doi: 10.3389/fpubh.2019.00332
pmc: PMC6908886
doi:

Types de publication

Systematic Review

Langues

eng

Pagination

332

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES007048
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES025888
Pays : United States

Informations de copyright

Copyright © 2019 Herting, Younan, Campbell and Chen.

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Auteurs

Megan M Herting (MM)

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States.
Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, United States.

Diana Younan (D)

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States.

Claire E Campbell (CE)

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States.

Jiu-Chiuan Chen (JC)

Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States.
Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles, CA, United States.

Classifications MeSH