Diet Associated with Inflammation and Alzheimer's Disease.
Alzheimer’s disease
diet
gluten sensitivity
inflammation
microbiome
oxidative stress
Journal
Journal of Alzheimer's disease reports
ISSN: 2542-4823
Titre abrégé: J Alzheimers Dis Rep
Pays: Netherlands
ID NLM: 101705500
Informations de publication
Date de publication:
16 Nov 2019
16 Nov 2019
Historique:
entrez:
24
12
2019
pubmed:
24
12
2019
medline:
24
12
2019
Statut:
epublish
Résumé
Neurocognitive disorders, such as Alzheimer's disease (AD), affect millions of people worldwide and are characterized by cognitive decline. Human and animal studies have shown that chronic immune response and inflammation are important factors in the pathogenesis of AD. Chronic inflammation can accelerate the aggregation of amyloid-β peptides and later hyperphosphorylation of tau proteins. The exact etiology of AD is not clear, but genetics and environmental factors, such as age, family history, and lifestyle are linked to neurodegenerative diseases. Lifestyle habits, such as poor diet, are associated with inflammation and could accelerate or slow down the progression of neurodegenerative diseases. Here we provide a review of the potential conditions and factors that stimulate the inflammatory processes in AD. An understanding of inflammatory mechanisms influencing the development of AD may help to protect against dementia and AD.
Identifiants
pubmed: 31867568
doi: 10.3233/ADR-190152
pii: ADR190152
pmc: PMC6918878
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
299-309Informations de copyright
© 2019 – IOS Press and the authors. All rights reserved.
Déclaration de conflit d'intérêts
The authors have no conflict of interest to report.
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