Alarm cue-mediated response and learning in zebrafish larvae.


Journal

Behavioural brain research
ISSN: 1872-7549
Titre abrégé: Behav Brain Res
Pays: Netherlands
ID NLM: 8004872

Informations de publication

Date de publication:
17 02 2020
Historique:
received: 02 07 2019
revised: 18 12 2019
accepted: 19 12 2019
pubmed: 25 12 2019
medline: 4 5 2021
entrez: 25 12 2019
Statut: ppublish

Résumé

We investigated the behavioural and learning response of zebrafish larvae to chemicals released by injured conspecifics (the alarm cue). Many aquatic vertebrates and invertebrates exhibit an innate antipredator response to alarm cues because in nature, they reliably indicate the presence of predators. Likewise, when an individual simultaneously perceives a novel odour and alarm cue, it learns to recognise the novel odour as a predator odour. Alarm cue-mediated behavioural response and learning have been reported in some fish and amphibians during early ontogeny, but in zebrafish, they have been described only for adults. In this study, we demonstrated that zebrafish at 12 and 24 days post fertilization exhibited reduced activity when exposed to alarm cue obtained by homogenised larvae of the same age, with this response being greater for the older zebrafish. In addition, we showed that 24-dpf zebrafish conditioned with alarm cue plus a novel odour learned to recognise the novel odour as a threat and responded to it with antipredator behaviour. The innate behavioural response and the learned response after conditioning may be used to develop paradigms with which to study anxiety, fear, stress, learning and memory in zebrafish larvae.

Identifiants

pubmed: 31870779
pii: S0166-4328(19)31024-1
doi: 10.1016/j.bbr.2019.112446
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

112446

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Tyrone Lucon-Xiccato (T)

Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy. Electronic address: tyrone.luconxiccato@unife.it.

Giuseppe Di Mauro (G)

Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.

Angelo Bisazza (A)

Dipartimento di Psicologia Generale, Università di Padova, Padova, Italy.

Cristiano Bertolucci (C)

Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy.

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Classifications MeSH