Maternal obesity and degree of glucose intolerance on neonatal hypoglycaemia and birth weight: a retrospective observational cohort study in women with gestational diabetes mellitus.
Gestational diabetes mellitus
Glucose intolerance
Maternal obesity
Neonatal hypoglycaemia
Risk factors
Journal
European journal of pediatrics
ISSN: 1432-1076
Titre abrégé: Eur J Pediatr
Pays: Germany
ID NLM: 7603873
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
01
11
2019
accepted:
16
12
2019
revised:
11
12
2019
pubmed:
25
12
2019
medline:
6
1
2021
entrez:
25
12
2019
Statut:
ppublish
Résumé
Gestational diabetes mellitus (GDM) is an increasing problem worldwide. Postnatal hypoglycaemia and excess foetal growth are known important metabolic complications of neonates born to women with diabetes. This retrospective cohort study aims to determine the influence of obesity and glucose intolerance on neonatal hypoglycaemia and birth weight over the 90th percentile (LGA). Data were abstracted from 303 patient medical records from singleton pregnancies diagnosed with GDM. Data were recorded during routine hospital visits. Demographic data were acquired by facilitated questionnaires and anthropometrics measured at the first antenatal appointment. Blood biochemical indices were recorded. Plasma glucose area under the curve (PG-AUC) was calculated from OGTT results as an index of glucose intolerance. OGTT results of 303 pregnant women aged between 33.6 years (29.8-37.7) diagnosed with GDM were described. Neonates of mothers with a BMI of over 30 kg/m
Identifiants
pubmed: 31873801
doi: 10.1007/s00431-019-03554-x
pii: 10.1007/s00431-019-03554-x
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
653-660Subventions
Organisme : University of Limerick
ID : EHS Deans scholarship
Organisme : HRI Health Research Institute, University of Limerick Ireland
ID : Strategic Research Fund 53305
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