Host- and Microbiota-Derived Extracellular Vesicles, Immune Function, and Disease Development.
diseases
gut microbiota derived extracellular vesicles
host derived extracellular vesicles
immune function
inflammation
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
22 Dec 2019
22 Dec 2019
Historique:
received:
11
11
2019
revised:
14
12
2019
accepted:
19
12
2019
entrez:
28
12
2019
pubmed:
28
12
2019
medline:
19
5
2020
Statut:
epublish
Résumé
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by eukaryotic cells both under physiological and pathological conditions. Genetic and environmental factors (diet, stress, etc.) affecting EV cargo, regulating EV release, and consequences on immunity will be covered. EVs are found in virtually all body fluids such as plasma, saliva, amniotic fluid, and breast milk, suggesting key roles in immune development and function at different life stages from in utero to aging. These will be reviewed here. Under pathological conditions, plasma EV levels are increased and exacerbate immune activation and inflammatory reaction. Sources of EV, cells targeted, and consequences on immune function and disease development will be discussed. Both pathogenic and commensal bacteria release EV, which are classified as outer membrane vesicles when released by Gram-negative bacteria or as membrane vesicles when released by Gram-positive bacteria. Bacteria derived EVs can affect host immunity with pathogenic bacteria derived EVs having pro-inflammatory effects of host immune cells while probiotic derived EVs mostly shape the immune response towards tolerance.
Identifiants
pubmed: 31877909
pii: ijms21010107
doi: 10.3390/ijms21010107
pmc: PMC6982009
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Australian Research Council
ID : 160100627
Organisme : a'Beckett foundation
ID : fellowship
Références
Nat Med. 2017 Jan;23(1):107-113
pubmed: 27892954
Front Microbiol. 2016 May 11;7:705
pubmed: 27242727
Microb Pathog. 2017 Sep;110:1-6
pubmed: 28634130
Adv Immunol. 2014;121:91-119
pubmed: 24388214
Diabetes. 2008 Jun;57(6):1470-81
pubmed: 18305141
Thromb Res. 2000 May 15;98(4):257-68
pubmed: 10822072
Am J Pathol. 2005 Jan;166(1):295-302
pubmed: 15632021
Crit Rev Microbiol. 2018 May;44(3):258-273
pubmed: 28741415
Blood. 2000 Feb 1;95(3):930-5
pubmed: 10648405
Sci Rep. 2015 Oct 29;5:15878
pubmed: 26510393
mBio. 2018 Apr 10;9(2):
pubmed: 29636428
Adv Parasitol. 2019;104:39-112
pubmed: 31030771
Exp Mol Med. 2018 Feb 23;50(2):e450
pubmed: 29472701
Br J Anaesth. 2012 Oct;109(4):503-13
pubmed: 22952169
FASEB J. 2015 Feb;29(2):684-95
pubmed: 25392266
Science. 2008 Feb 29;319(5867):1244-7
pubmed: 18309083
Cell Host Microbe. 2012 Oct 18;12(4):509-20
pubmed: 22999859
J Allergy Clin Immunol. 2016 Feb;137(2):507-516.e8
pubmed: 26433560
Science. 2013 Aug 2;341(6145):569-73
pubmed: 23828891
J Neurotrauma. 2018 Nov 15;35(22):2684-2690
pubmed: 29969943
Front Immunol. 2014 Mar 28;5:125
pubmed: 24734032
J Clin Invest. 1999 Jul;104(1):93-102
pubmed: 10393703
Br J Haematol. 1967 May;13(3):269-88
pubmed: 6025241
Trends Cell Biol. 2008 May;18(5):199-209
pubmed: 18396047
Silence. 2010 Mar 01;1(1):7
pubmed: 20226005
Semin Cell Dev Biol. 2017 Jul;67:48-55
pubmed: 28104520
Acta Biomater. 2019 Jun;91:248-257
pubmed: 31003032
Allergy Asthma Immunol Res. 2018 Sep;10(5):516-532
pubmed: 30088371
Nat Commun. 2018 Apr 11;9(1):1379
pubmed: 29643357
Sci Rep. 2015 Nov 10;5:16314
pubmed: 26553743
Nat Rev Microbiol. 2015 Oct;13(10):620-30
pubmed: 26324094
Cell Host Microbe. 2014 May 14;15(5):623-35
pubmed: 24746552
Clin Transl Med. 2018 May 31;7(1):14
pubmed: 29855735
Nature. 2013 Dec 19;504(7480):451-5
pubmed: 24226773
J Clin Invest. 1998 Jul 1;102(1):136-44
pubmed: 9649567
Mass Spectrom Rev. 2008 Nov-Dec;27(6):535-55
pubmed: 18421767
Am J Physiol Gastrointest Liver Physiol. 2019 Nov 1;317(5):G618-G624
pubmed: 31509432
J Dairy Sci. 2018 Oct;101(10):8662-8671
pubmed: 30100498
Cell Microbiol. 2016 Nov;18(11):1508-1517
pubmed: 27529760
Nature. 2018 Aug;560(7718):382-386
pubmed: 30089911
Genes Dev. 2012 Jun 15;26(12):1287-99
pubmed: 22713869
PLoS Pathog. 2016 Jun 13;12(6):e1005672
pubmed: 27295279
J Cell Sci. 2002 Jun 15;115(Pt 12):2505-15
pubmed: 12045221
Nat Med. 2016 Oct 06;22(10):1079-1089
pubmed: 27711063
Crit Care Med. 2005 Nov;33(11):2540-6
pubmed: 16276178
Nat Med. 2003 Aug;9(8):1020-5
pubmed: 12858167
J Immunother. 2003 Sep-Oct;26(5):440-50
pubmed: 12973033
J Immunol. 2014 Oct 1;193(7):3378-87
pubmed: 25187656
J Immunol. 2013 Jan 15;190(2):669-77
pubmed: 23241892
Thromb Res. 2015 Feb;135 Suppl 1:S23-5
pubmed: 25903528
FASEB J. 2017 Jul;31(7):2817-2827
pubmed: 28314769
Am J Cancer Res. 2011;1(1):98-110
pubmed: 21969178
Front Microbiol. 2017 Dec 08;8:2440
pubmed: 29276507
Front Physiol. 2018 Oct 31;9:1534
pubmed: 30429801
PLoS Pathog. 2010 Jul 29;6(7):e1001021
pubmed: 20686652
Cell Host Microbe. 2016 Aug 10;20(2):202-14
pubmed: 27476413
Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12204-9
pubmed: 20566854
Biochem Soc Trans. 2019 Feb 28;47(1):273-280
pubmed: 30647137
Cell Rep. 2016 Jun 21;15(12):2809-24
pubmed: 27332875
Nat Cell Biol. 2007 Jun;9(6):654-9
pubmed: 17486113
Eur J Microbiol Immunol (Bp). 2016 Dec 01;6(4):253-271
pubmed: 27980855
PLoS One. 2015 Jan 12;10(1):e0116896
pubmed: 25581302
Nature. 2009 Oct 29;461(7268):1282-6
pubmed: 19865172
Arthritis Rheumatol. 2015 Jun;67(6):1646-56
pubmed: 25914377
Eur J Cell Biol. 2007 Jul;86(7):405-15
pubmed: 17601634
Neurology. 2001 May 22;56(10):1319-24
pubmed: 11376181
J Immunol. 2017 Mar 1;198(5):2172-2181
pubmed: 28100682
PLoS One. 2012;7(6):e39743
pubmed: 22761885
Front Immunol. 2017 Aug 25;8:1017
pubmed: 28890719
Oncotarget. 2015 May 10;6(13):11327-41
pubmed: 25857301
Nat Immunol. 2017 May;18(5):552-562
pubmed: 28346408
J Immunol. 2009 Dec 1;183(11):7023-30
pubmed: 19915051
Sci Rep. 2016 Dec 05;6:37871
pubmed: 27917875
Cancer Treat Rev. 2012 May;38(3):226-34
pubmed: 21757296
J Thromb Haemost. 2003 Jul;1(7):1655-62
pubmed: 12871302
Appl Environ Microbiol. 1990 Jun;56(6):1960-2
pubmed: 16348232
Science. 2012 Jun 8;336(6086):1268-73
pubmed: 22674334
Nat Commun. 2015 Apr 01;6:6734
pubmed: 25828455
Prog Neurobiol. 2010 Jun;91(2):140-51
pubmed: 20117166
J Extracell Vesicles. 2015 May 14;4:27066
pubmed: 25979354
Front Immunol. 2017 May 12;8:548
pubmed: 28553291
Mol Hum Reprod. 2004 Jan;10(1):55-63
pubmed: 14665707
Front Immunol. 2018 Jun 28;9:1486
pubmed: 30002658
Leukemia. 2006 May;20(5):847-56
pubmed: 16453000
FASEB J. 2009 Oct;23(10):3449-58
pubmed: 19535685
J Biol Chem. 2005 Aug 5;280(31):28439-50
pubmed: 15870081
PLoS Pathog. 2014 Mar 20;10(3):e1003839
pubmed: 24651155
Dev Cell. 2019 May 6;49(3):347-360
pubmed: 31063754
Oncotarget. 2016 Mar 22;7(12):14639-58
pubmed: 26840259
mBio. 2018 Nov 20;9(6):
pubmed: 30459192
Microcirculation. 2019 Feb;26(2):e12485
pubmed: 29923276
Mult Scler. 2016 Dec;22(14):1883-1887
pubmed: 26931477
Sci Transl Med. 2019 Aug 28;11(507):
pubmed: 31462512
Science. 2008 Dec 5;322(5907):1562-5
pubmed: 19056990
Immunity. 2019 Feb 19;50(2):432-445.e7
pubmed: 30683619
JAMA. 2004 Mar 3;291(9):1127-31
pubmed: 14996783
PLoS Pathog. 2010 Jan 29;6(1):e1000744
pubmed: 20126448
Cell. 2016 Jun 2;165(6):1332-1345
pubmed: 27259147
Immunol Cell Biol. 2018 May 8;:null
pubmed: 29738615
Immunity. 2019 Aug 20;51(2):285-297.e5
pubmed: 31272808
JAMA. 2004 Jun 2;291(21):2542-4
pubmed: 15173142
Annu Rev Cell Dev Biol. 2014;30:255-89
pubmed: 25288114
Clin Exp Allergy. 2019 Jan;49(1):68-81
pubmed: 30288827
Curr Opin Pediatr. 2014 Jun;26(3):377-82
pubmed: 24759226
Leukemia. 2009 Sep;23(9):1643-9
pubmed: 19369960
Int J Mol Sci. 2019 Apr 08;20(7):null
pubmed: 30965555
Proteomics. 2019 Apr;19(8):e1800167
pubmed: 30793499
Ann Transl Med. 2017 May;5(Suppl 1):S16
pubmed: 28567398
Cell Host Microbe. 2018 Jun 13;23(6):705-715
pubmed: 29902436
Gut. 2020 Jan;69(1):191-193
pubmed: 30518529
J Immunol. 2009 Jul 1;183(1):340-51
pubmed: 19542445
Cell Mol Immunol. 2014 Nov;11(6):548-63
pubmed: 24954226
J Cell Biol. 2002 Nov 25;159(4):625-35
pubmed: 12438417
PLoS Pathog. 2010 Jan 15;6(1):e1000724
pubmed: 20090836
Int J Mol Sci. 2019 Mar 25;20(6):null
pubmed: 30934547
Nat Commun. 2015 Jun 23;6:7320
pubmed: 26102221
Nat Commun. 2016 Apr 14;7:11220
pubmed: 27075392
Blood. 1997 Feb 15;89(4):1121-32
pubmed: 9028933
Nat Rev Immunol. 2015 Jun;15(6):375-87
pubmed: 25976515
Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1321-6
pubmed: 18195363
PLoS Med. 2005 Sep;2(9):e245
pubmed: 16104828
BMC Microbiol. 2017 Mar 14;17(1):66
pubmed: 28288575
J Reprod Immunol. 2017 Feb;119:98-106
pubmed: 27613663