Favorable 90-Day Mortality in Obese Caucasian Patients with Septic Shock According to the Sepsis-3 Definition.

90-day mortality Sepsis-3 definition Survival predictors obesity risk stratification septic shock

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
24 Dec 2019
Historique:
received: 23 11 2019
revised: 04 12 2019
accepted: 20 12 2019
entrez: 28 12 2019
pubmed: 28 12 2019
medline: 28 12 2019
Statut: epublish

Résumé

Septic shock is a frequent life-threatening condition and a leading cause of mortality in intensive care units (ICUs). Previous investigations have reported a potentially protective effect of obesity in septic shock patients. However, prior results have been inconsistent, focused on short-term in-hospital mortality and inadequately adjusted for confounders, and they have rarely applied the currently valid Sepsis-3 definition criteria for septic shock. This investigation examined the effect of obesity on 90-day mortality in patients with septic shock selected from a prospectively enrolled cohort of septic patients. A total of 352 patients who met the Sepsis-3 criteria for septic shock were enrolled in this study. Body-mass index (BMI) was used to divide the cohort into 24% obese (BMI ≥ 30 kg/m

Identifiants

pubmed: 31878238
pii: jcm9010046
doi: 10.3390/jcm9010046
pmc: PMC7019854
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : University of Goettingen
ID : Open Access Publication Fund

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Auteurs

Caspar Mewes (C)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Carolin Böhnke (C)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Tessa Alexander (T)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Benedikt Büttner (B)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

José Hinz (J)

Department of Anesthesiology and Intensive Care Medicine, Klinikum Region Hannover, D-30459 Hannover, Germany.

Aron-Frederik Popov (AF)

Department of Thoracic and Cardiovascular Surgery, University Medical Center, Eberhard Karls University, D-72076 Tuebingen, Germany.

Michael Ghadimi (M)

Department of General and Visceral Surgery, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Tim Beißbarth (T)

Institute of Medical Bioinformatics, University Medical Center, Georg August University, D-37077 Goettingen, Germany.

Dirk Raddatz (D)

Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Konrad Meissner (K)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Michael Quintel (M)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Ingo Bergmann (I)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Ashham Mansur (A)

Department of Anesthesiology, University Medical Center, Georg August University, D-37075 Goettingen, Germany.

Classifications MeSH