Pathological complete response by advanced hepatocellular carcinoma with massive macrovascular invasion to hepatic arterial infusion chemotherapy: a case report.
Aged
Antineoplastic Combined Chemotherapy Protocols
/ administration & dosage
Carcinoma, Hepatocellular
/ blood supply
Cisplatin
/ administration & dosage
Combined Modality Therapy
Fluorouracil
/ administration & dosage
Hepatic Artery
/ pathology
Humans
Infusions, Intra-Arterial
Liver Neoplasms
/ blood supply
Male
Treatment Outcome
Venous Thrombosis
/ pathology
Complete response
Hepatic arterial infusion chemotherapy
Hepatocellular carcinoma
Macrovascular invasion
Journal
World journal of surgical oncology
ISSN: 1477-7819
Titre abrégé: World J Surg Oncol
Pays: England
ID NLM: 101170544
Informations de publication
Date de publication:
26 Dec 2019
26 Dec 2019
Historique:
received:
20
09
2019
accepted:
17
12
2019
entrez:
28
12
2019
pubmed:
28
12
2019
medline:
30
5
2020
Statut:
epublish
Résumé
Advanced hepatocellular carcinoma (HCC) with macrovascular invasion has an extremely dismal prognosis. We report a rare case of multiple HCC with tumor thrombosis in the portal vein and inferior vena cava that was initially treated with hepatic arterial infusion chemotherapy (HAIC); later resection revealed pathological complete response. A 75-year-old man presented with HCC in his right liver, with tumor thrombosis growing to the right portal vein and the inferior vena cava, and bilateral intrahepatic liver metastases. He underwent HAIC (5-fluorouracil [170 mg/m HAIC can be an effective alternative treatment for advanced HCC with macrovascular invasion.
Sections du résumé
BACKGROUND
BACKGROUND
Advanced hepatocellular carcinoma (HCC) with macrovascular invasion has an extremely dismal prognosis. We report a rare case of multiple HCC with tumor thrombosis in the portal vein and inferior vena cava that was initially treated with hepatic arterial infusion chemotherapy (HAIC); later resection revealed pathological complete response.
CASE PRESENTATION
METHODS
A 75-year-old man presented with HCC in his right liver, with tumor thrombosis growing to the right portal vein and the inferior vena cava, and bilateral intrahepatic liver metastases. He underwent HAIC (5-fluorouracil [170 mg/m
CONCLUSIONS
CONCLUSIONS
HAIC can be an effective alternative treatment for advanced HCC with macrovascular invasion.
Identifiants
pubmed: 31878937
doi: 10.1186/s12957-019-1772-8
pii: 10.1186/s12957-019-1772-8
pmc: PMC6933654
doi:
Substances chimiques
Cisplatin
Q20Q21Q62J
Fluorouracil
U3P01618RT
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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