T-cell lymphoproliferative processes in the spleen.

Hepatosplenic T cell lymphoma Splenic T-cell lymphoproliferative disorders

Journal

Seminars in diagnostic pathology
ISSN: 0740-2570
Titre abrégé: Semin Diagn Pathol
Pays: United States
ID NLM: 8502262

Informations de publication

Date de publication:
Jan 2020
Historique:
pubmed: 28 12 2019
medline: 18 11 2020
entrez: 28 12 2019
Statut: ppublish

Résumé

T-cell lymphoproliferative processes in the spleen are rare and it is important to study normal T cell subsets in the spleen to understand the splenic milieu in which they arise. True malignant T-cell processes including hepatosplenic T-cell lymphoma and T-cell large granular lymphocytic leukemia occur in the spleen, but other atypical reactive T-cell proliferations and those of uncertain significance also have been described. Proper distinction of florid T cell responses from malignant T-cell neoplasms has important therapeutic implications for the patient.

Identifiants

pubmed: 31879048
pii: S0740-2570(19)30111-X
doi: 10.1053/j.semdp.2019.12.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

47-56

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Nadine S Aguilera (NS)

Department of Pathology, University of Virginia Health System, Charlottesville VA 22908-0214, United States. Electronic address: na2d@virginia.edu.

Aaron Auerbach (A)

Joint Pathology Center, Silver Spring MD, United States.

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Classifications MeSH