Safety evaluation of the excessive intake of
Bacillus subtilis C-3102
Bone mineral density
Excessive intake
Gut microbiota
Safety evaluation
Journal
Toxicology reports
ISSN: 2214-7500
Titre abrégé: Toxicol Rep
Pays: Ireland
ID NLM: 101630272
Informations de publication
Date de publication:
2020
2020
Historique:
received:
17
12
2018
revised:
11
11
2019
accepted:
13
11
2019
entrez:
28
12
2019
pubmed:
28
12
2019
medline:
28
12
2019
Statut:
epublish
Résumé
Continuous intake of A total of 69 individuals provided an informed consent, and 44 subjects who met the inclusion criteria were allocated to either the The final analysis included data from 22 subjects (9 men, 13 women; age, 46.1 ± 13.8 years) in the C-3102 group and 22 subjects (9 men, 13 women; age, 46.1 ± 13.5 years) in the P group. The results revealed no medical-related problems in both C-3102 and P groups. This study proved the safety of 4-week continuous consumption of an excessive amount of
Identifiants
pubmed: 31879597
doi: 10.1016/j.toxrep.2019.11.009
pii: S2214-7500(18)30760-1
pmc: PMC6920086
doi:
Types de publication
Journal Article
Langues
eng
Pagination
46-58Informations de copyright
© 2019 The Authors.
Déclaration de conflit d'intérêts
This study was sponsored by the following companies: Asahi Calpis Wellness Co., Ltd funded the study implementation and manuscript writing. M. H., H. K., R. T., I. N., and M. Y. are members of Asahi Calpis Wellness Co., Ltd. that entrusted ORTHOMEDICO, Inc. T. H. and S. I., who are members of ORTHOMEDICO Inc., were involved in the planning of the study, the study implementation, and manuscript writing. The study was conducted by both Asahi Calpis Wellness Co., Ltd and ORTHOMEDICO Inc. Furthermore, T. T. (MD) is the principal investigator who monitors all subjects’ conditions.
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