Pixantrone plus rituximab versus gemcitabine plus rituximab in patients with relapsed aggressive B-cell non-Hodgkin lymphoma not eligible for stem cell transplantation: a phase 3, randomized, multicentre trial (PIX306).
DLBCL
FL grade 3
gemcitabine
pixantrone
rituximab
Journal
British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544
Informations de publication
Date de publication:
01 2020
01 2020
Historique:
received:
27
06
2019
accepted:
23
09
2019
pubmed:
28
12
2019
medline:
6
8
2020
entrez:
28
12
2019
Statut:
ppublish
Résumé
PIX306 was a phase 3, randomised, single-blind, multicentre trial conducted in adult patients with diffuse large B-cell lymphoma (DLBCL) or follicular lymphoma (FL) grade 3 who relapsed after ≥1 rituximab-containing regimen and were not eligible for a stem cell transplant. Patients were randomised 1:1 to pixantrone 50 mg/m
Substances chimiques
Isoquinolines
0
Deoxycytidine
0W860991D6
Rituximab
4F4X42SYQ6
pixantrone
F5SXN2KNMR
Gemcitabine
0
Types de publication
Clinical Trial, Phase III
Journal Article
Multicenter Study
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
240-248Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2019 British Society for Haematology and John Wiley & Sons Ltd.
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