Characteristics and influence of Mycoplasma/Ureaplasma cultures in amniotic fluid on perinatal outcomes.
Adult
Amniocentesis
Amniotic Fluid
/ microbiology
Female
Fetal Membranes, Premature Rupture
/ microbiology
Humans
Mycoplasma
/ isolation & purification
Mycoplasma Infections
/ diagnosis
Pregnancy
Pregnancy Complications, Infectious
/ diagnosis
Pregnancy Outcome
Ureaplasma
/ isolation & purification
Ureaplasma Infections
/ diagnosis
Mycoplasma hominis
Ureaplasma urealyticum
amniocentesis
bronchopulmonary dysplasia
intrauterine infection
Journal
The journal of obstetrics and gynaecology research
ISSN: 1447-0756
Titre abrégé: J Obstet Gynaecol Res
Pays: Australia
ID NLM: 9612761
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
22
09
2019
accepted:
07
12
2019
pubmed:
29
12
2019
medline:
15
12
2020
entrez:
29
12
2019
Statut:
ppublish
Résumé
To investigate the effects of Mycoplasma/Ureaplasma cultured in amniotic fluid on perinatal characteristics in preterm delivery between 22 and 33 weeks of gestation. The study was conducted in a tertiary perinatal center and involved 38 pregnant women who had undergone amniocentesis to evaluate intrauterine infection due to preterm labor or premature rupture of membranes. The subjects were divided into three groups based on the culture results: negative (Negative Group, n = 24), positive for Mycoplasma/Ureaplasma (M/U Group, n = 6), and positive for other pathogens (Other Pathogens Group, n = 8). One-way analysis of variance was used to compare the three groups. The incidence of histological chorioamnionitis and neonatal sepsis was significantly different among the three groups (the Negative Group and the Other Pathogens Group, P < 0.01; the M/U Group and the Other Pathogens Group, P = 0.03). In the M/U Group, no infants had sepsis, severe intraventricular hemorrhage, cystic periventricular leukomalacia, or poor neurological outcomes, but one infant developed bronchopulmonary dysplasia and needed home oxygen treatment. Although one died of gastrorrhexis, the remaining five patients had normal brain magnetic resonance imaging findings and developed normally. The presence of Mycoplasma/Ureaplasma isolated from amniotic fluid did not cause neonatal sepsis or poor prognosis. In some infants, there was no histological chorioamnionitis in the placenta. These pathogens thus seem to be less invasive than any other microbes with respect to perinatal outcomes.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
389-395Subventions
Organisme : Miyazaki University Hospital
Informations de copyright
© 2019 Japan Society of Obstetrics and Gynecology.
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