Management of Advanced and Metastatic Prostate Cancer: A Need for a Sub-Saharan Guideline.


Journal

Journal of oncology
ISSN: 1687-8450
Titre abrégé: J Oncol
Pays: Egypt
ID NLM: 101496537

Informations de publication

Date de publication:
2019
Historique:
received: 03 08 2019
revised: 13 11 2019
accepted: 21 11 2019
entrez: 31 12 2019
pubmed: 31 12 2019
medline: 31 12 2019
Statut: epublish

Résumé

The estimated incidence rate of prostate cancer in Africa was 22.0/100,000 in 2016. The International Agency for Research on Cancer (IARC) has cited prostate cancer as a growing health threat in Africa with approximated 28,006 deaths in 2010 and estimated 57,048 deaths in 2030. The exact incidence of advanced and metastatic prostate cancer is not known in sub-Saharan Africa. Hospital-based reports from the region have shown a rising trend with most patients presenting with advanced or metastatic disease. The management of advanced and metastatic prostate cancer is challenging. The available international guidelines may not be cost-effective for an African population. The most efficient approach in the region has been surgical castration by bilateral orchidectomy or pulpectomy. Medical androgen deprivation therapy is expensive and may not be available. Patients with metastatic castrate-resistant prostate cancer tend to be palliated due to the absence or cost of chemotherapy or second-line androgen deprivation therapy in most of Africa. A cost-effective guideline for developing nations to address the rising burden of advanced prostate cancer is warranted at this moment.

Identifiants

pubmed: 31885569
doi: 10.1155/2019/1785428
pmc: PMC6915139
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1785428

Informations de copyright

Copyright © 2019 Ayun Cassell et al.

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest regarding this article.

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Auteurs

Ayun Cassell (A)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Bashir Yunusa (B)

Department of Surgery, Liberia College of Physicians and Surgeons, Monrovia, Liberia.

Mohamed Jalloh (M)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Medina Ndoye (M)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Mouhamadou M Mbodji (MM)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Abdourahmane Diallo (A)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Saint Charles Kouka (SC)

UFR Sante, Université de Thiès, Thiès, Senegal.

Issa Labou (I)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Lamine Niang (L)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Serigne M Gueye (SM)

Department of Urology and Andrology, Hopital General de Grand Yoff, Dakar, Senegal.

Classifications MeSH