Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation.


Journal

Stem cells international
ISSN: 1687-966X
Titre abrégé: Stem Cells Int
Pays: United States
ID NLM: 101535822

Informations de publication

Date de publication:
2019
Historique:
received: 05 07 2019
revised: 17 10 2019
accepted: 20 11 2019
entrez: 31 12 2019
pubmed: 31 12 2019
medline: 31 12 2019
Statut: epublish

Résumé

Mesenchymal stem cells (MSCs) emerged as a promising therapy for tendon pathologies. Microfragmented adipose tissue ( Cell viability and proliferation were evaluated after 48 hours of transwell coculture of TCs and autologous IL-1 In this in vitro model of tendon cell inflammation, the paracrine action of

Sections du résumé

BACKGROUND BACKGROUND
Mesenchymal stem cells (MSCs) emerged as a promising therapy for tendon pathologies. Microfragmented adipose tissue (
METHODS METHODS
Cell viability and proliferation were evaluated after 48 hours of transwell coculture of TCs and autologous
RESULTS RESULTS
IL-1
CONCLUSIONS CONCLUSIONS
In this in vitro model of tendon cell inflammation, the paracrine action of

Identifiants

pubmed: 31885616
doi: 10.1155/2019/5620286
pmc: PMC6915130
doi:

Types de publication

Journal Article

Langues

eng

Pagination

5620286

Informations de copyright

Copyright © 2019 Marco Viganò et al.

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest regarding the publication of this paper.

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Auteurs

Marco Viganò (M)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Gaia Lugano (G)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Carlotta Perucca Orfei (C)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Alessandra Menon (A)

Laboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.
1st Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy.

Enrico Ragni (E)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Alessandra Colombini (A)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Paola De Luca (P)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Pietro Randelli (P)

Laboratory of Applied Biomechanics, Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via Mangiagalli 31, 20133 Milan, Italy.
1st Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milan, Italy.

Laura de Girolamo (L)

Orthopedics Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Classifications MeSH