Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia.


Journal

Case reports in hematology
ISSN: 2090-6560
Titre abrégé: Case Rep Hematol
Pays: United States
ID NLM: 101576456

Informations de publication

Date de publication:
2019
Historique:
received: 31 08 2019
accepted: 31 10 2019
entrez: 31 12 2019
pubmed: 31 12 2019
medline: 31 12 2019
Statut: epublish

Résumé

A 34-year-old woman was diagnosed with acute promyelocytic leukemia. Chemotherapy was administered following the JALSG APL204 protocol. Induction therapy with all-trans retinoic acid resulted in complete remission on day 49. She developed coccygeal pain from day 18, which spread to the spine and cheekbones and lasted 5 weeks. She had similar bone pain on days 7-10 of the first consolidation therapy and on days 4-12 of the second consolidation therapy. Oral loxoprofen was prescribed for pain relief. On day 33 of the third consolidation, white blood cell and neutrophil counts were 320/

Identifiants

pubmed: 31885950
doi: 10.1155/2019/1616237
pmc: PMC6900957
doi:

Types de publication

Case Reports

Langues

eng

Pagination

1616237

Informations de copyright

Copyright © 2019 Yuta Inagawa et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this article.

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Auteurs

Yuta Inagawa (Y)

Department of Hematology, Japan Community Healthcare Organization (JCHO) Tokyo Yamate Medical Center, Tokyo, Japan.
Department of Internal Medicine, JCHO Tokyo Yamate Medical Center, Tokyo, Japan.

Yukiko Komeno (Y)

Department of Hematology, Japan Community Healthcare Organization (JCHO) Tokyo Yamate Medical Center, Tokyo, Japan.

Satoshi Saito (S)

Department of Gastroenterology, JCHO Tokyo Yamate Medical Center, Tokyo, Japan.

Yuji Maenohara (Y)

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Tetsuro Yamagishi (T)

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medicine and Dental Sciences, Niigata, Japan.

Hiroyuki Kawashima (H)

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medicine and Dental Sciences, Niigata, Japan.

Taku Saito (T)

Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Keiko Abe (K)

Department of Pathology, JCHO Tokyo Yamate Medical Center, Tokyo, Japan.

Kuniko Iihara (K)

Department of Pathology, JCHO Tokyo Yamate Medical Center, Tokyo, Japan.

Yasumasa Hatada (Y)

Department of Gastroenterology, JCHO Tokyo Yamate Medical Center, Tokyo, Japan.

Tomiko Ryu (T)

Department of Hematology, Japan Community Healthcare Organization (JCHO) Tokyo Yamate Medical Center, Tokyo, Japan.

Classifications MeSH