Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture.

Bone Density Humans Lumbar Vertebrae / diagnostic imaging Spinal Fractures / diagnostic imaging Tomography, X-Ray Computed
BIOMECHANICS BONE QCT/μCT FRACTURE RISK ASSESSMENT GENERAL POPULATION STUDIES OSTEOPOROSIS

Journal

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
ISSN: 1523-4681
Titre abrégé: J Bone Miner Res
Pays: United States
ID NLM: 8610640

Informations de publication

Date de publication:
04 2020
Historique:
received: 26 02 2019
revised: 12 12 2019
accepted: 14 12 2019
pubmed: 31 12 2019
medline: 29 7 2021
entrez: 31 12 2019
Statut: ppublish

Résumé

The spatial heterogeneity in trabecular bone density within the vertebral centrum is associated with vertebral strength and could explain why volumetric bone mineral density (vBMD) exhibits low sensitivity in identifying fracture risk. This study evaluated whether the heterogeneity and spatial distribution of trabecular vBMD are associated with prevalent vertebral fracture. We examined the volumetric quantitative computed tomography (QCT) scans of the L

Identifiants

DOI: 10.1002/jbmr.3946 PMID: 31886907 PMC: PMC7145746
pubmed: 31886907
doi: 10.1002/jbmr.3946
pmc: PMC7145746
mid: NIHMS1551219
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

641-648

Subventions

Organisme : NIAMS NIH HHS
ID : R01 AR054620
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG041658
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR053986
Pays : United States
Organisme : NHLBI NIH HHS
ID : HHSN268201500001I
Pays : United States

Informations de copyright

© 2019 American Society for Bone and Mineral Research.

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Auteurs

Jarred Kaiser (J)

Department of Mechanical Engineering, Boston University, Boston, MA, USA.
ORCID: 0000-0001-9373-2961

Brett Allaire (B)

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Paul M Fein (PM)

Department of Mechanical Engineering, Boston University, Boston, MA, USA.

Darlene Lu (D)

Department of Biostatistics, Boston University, Boston, MA, USA.

Alexander Adams (A)

Department of Mechanical Engineering, Boston University, Boston, MA, USA.

Douglas P Kiel (DP)

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Department of Medicine, Harvard Medical School, Boston, MA, USA.
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, USA.

Mohamed Jarraya (M)

Department of Radiology, Boston University School of Medicine, Boston, MA, USA.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Ali Guermazi (A)

Department of Radiology, Boston University School of Medicine, Boston, MA, USA.

Serkalem Demissie (S)

Department of Biostatistics, Boston University, Boston, MA, USA.

Elizabeth J Samelson (EJ)

Department of Biostatistics, Boston University, Boston, MA, USA.
Department of Medicine, Harvard Medical School, Boston, MA, USA.
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Roslindale, MA, USA.
ORCID: 0000-0003-1086-1560

Mary L Bouxsein (ML)

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Department of Orthopedic Surgery, Harvard Medical School, Boston, MA, USA.

Elise F Morgan (EF)

Department of Mechanical Engineering, Boston University, Boston, MA, USA.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Densité osseuse › Heterogeneity and Spatial Distribution of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Heterogeneity and Spatial Distribution of...
questionsmedicales.fr › Appareil locomoteur › Squelette › Rachis › Vertèbres lombales › Heterogeneity and Spatial Distribution of...
questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Fractures du rachis › Heterogeneity and Spatial Distribution of...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Tomographie à rayons X › Tomodensitométrie › Heterogeneity and Spatial Distribution of...