A novel detrimental homozygous mutation in the WFS1 gene in two sisters from nonconsanguineous parents with untreated diabetes insipidus.

WFS1 gene Wolfram syndrome diabetes insipidus diabetes mellitus novel mutation

Journal

Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 20 06 2019
revised: 01 09 2019
accepted: 15 09 2019
entrez: 2 1 2020
pubmed: 2 1 2020
medline: 2 1 2020
Statut: epublish

Résumé

Given the limited lifespan and with the recent progress in experimental treatments for WS, timely diagnosis and multidisciplinary treatment for DI/DM, hydronephrosis, and visual/psychiatric status-maintaining quality of life-are of crucial importance.

Identifiants

pubmed: 31893057
doi: 10.1002/ccr3.2494
pii: CCR32494
pmc: PMC6935624
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2355-2357

Informations de copyright

© 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Déclaration de conflit d'intérêts

All authors declare no conflict of interest.

Références

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Auteurs

Dimitrios T Papadimitriou (DT)

Department of Pediatric Endocrinology & Diabetes Athens Medical Center Athens Greece.

Kleanthis Kleanthous (K)

Department of Pediatric Endocrinology & Diabetes Athens Medical Center Athens Greece.
Department of Pediatric Endocrinology and Diabetes Attikon University Hospital Athens Greece.

Emmanouil Manolakos (E)

Access to Genome Athens-Thessaloniki Athens Greece.

Anatoly Tiulpakov (A)

Department and Laboratory of Inherited Endocrine Disorders Endocrinology Research Centre Moscow Russia.

Thomas Nikolopoulos (T)

Department of Pediatric Otorhinolaryngology Attikon University Hospital Athens Greece.

Alexandros Delides (A)

Department of Pediatric Otorhinolaryngology Attikon University Hospital Athens Greece.
Department of Pediatric Otorhinolaryngology Athens Medical Center Athens Greece.

Gerasimos Voros (G)

Department of Pediatric Ophthalmology Athens Medical Center Athens Greece.

Argyrios Dinopoulos (A)

Department of Pediatric Neurology Attikon University Hospital Athens Greece.

George Zoupanos (G)

Department of Pediatric Urology Athens Medical Center Athens Greece.

Anastasios Papadimitriou (A)

Department of Pediatric Endocrinology and Diabetes Attikon University Hospital Athens Greece.

Georgios Mastorakos (G)

Endocrine Unit Aretaieion Hospital Medical School University of Athens Athens Greece.

Fumihiko Urano (F)

Washington University School of Medicine St. Louis MO.

Classifications MeSH