Outcome of radioiodine therapy in thyroid cancer patients with recent contrasted computed tomography.


Journal

Nuclear medicine communications
ISSN: 1473-5628
Titre abrégé: Nucl Med Commun
Pays: England
ID NLM: 8201017

Informations de publication

Date de publication:
Mar 2020
Historique:
pubmed: 3 1 2020
medline: 16 12 2020
entrez: 3 1 2020
Statut: ppublish

Résumé

To document the outcome of radioiodine therapy (RIT) in differentiated thyroid cancer (DTC) patients with recent contrasted computed tomography (CCT). Eighteen patients with DTC and recent thyroidectomy who underwent RIT within 90 days after a CCT were included. Disease status following RIT and whether the expected response to RIT was achieved were documented. Disease status was classified into one of three categories based on the patient's thyroglobuline level, radioiodine scan (RIS), and other imaging modalities: no evidence of disease (NED), microscopic residual disease (MRD), or gross residual disease (GRD). Expected response to RIT was based on the overall interpretation of the referring physicians of follow up thyroglobuline values, RIS findings and clinical assessment as reflected in progress notes. Follow-up stimulated thyroglobuline and (or) RIS was performed on average 10.8 months after RIT (median 12 months). The last progress note reviewed was on average 33.3 months after RIT (median 31 months). There were 12 patients with NED, two with MRD and four with GRD. Expected response to RIT was achieved in 17 patients. In one patient, the effectiveness of RIT could not be determined. RIT in postthyroidectomy setting can be successfully performed within 90 days after CCT. Further research is needed to confirm our findings.

Identifiants

pubmed: 31895755
doi: 10.1097/MNM.0000000000001137
pii: 00006231-202003000-00008
doi:

Substances chimiques

Iodine Radioisotopes 0
Radiopharmaceuticals 0
Thyroglobulin 9010-34-8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

228-234

Références

Amdur RJ, Mazzeferri EL. Amdur RJ, Mazzeferri EL. Intravenous iodinated contrast effects iodine uptake for months. Essentials of Thyroid Cancer Management. 2005, New York: Springer211–213
Perros P, Boelaert K, Colley S, Evans C, Evans RM, Gerrard Ba G, et al.; British Thyroid Association. Guidelines for the management of thyroid cancer. Clin Endocrinol (Oxf). 2014; 81Suppl 11–122
Silberstein EB, Alavi A, Balon HR, Clarke SE, Divgi C, Gelfand MJ, et al. The SNMMI practice guideline for therapy of thyroid disease with 131I 3.0. J Nucl Med. 2012; 53:1633–1651
Luster M, Clarke SE, Dietlein M, Lassmann M, Lind P, Oyen WJ, et al.; European Association of Nuclear Medicine (EANM). Guidelines for radioiodine therapy of differentiated thyroid cancer. Eur J Nucl Med Mol Imaging. 2008; 35:1941–1959
Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 american thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the american thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016; 26:1–133
Spratt DE, Zaki BI, Franc BL, Hartford AC, Osborne JR. ACR practice parameter for the performance of therapy with unsealed radiopharmaceutical sources. Clin Nucl Med. 2016; 41:106–117
Andresen NS, Buatti JM, Tewfik HH, Pagedar NA, Anderson CM, Watkins JM. Radioiodine ablation following thyroidectomy for differentiated thyroid cancer: literature review of utility, dose, and toxicity. Eur Thyroid J. 2017; 6:187–196
Jeong E, Yoon JK, Lee SJ, Soh EY, Lee J, An YS. Risk factors for indeterminate response after radioactive iodine therapy in patients with differentiated thyroid cancer. Clin Nucl Med. 2019; 44:714–718
Mishra A, Pradhan PK, Gambhir S, Sabaretnam M, Gupta A, Babu S. Preoperative contrast-enhanced computerized tomography should not delay radioiodine ablation in differentiated thyroid carcinoma patients. J Surg Res. 2015; 193:731–737
Padovani RP, Kasamatsu TS, Nakabashi CC, Camacho CP, Andreoni DM, Malouf EZ, et al. One month is sufficient for urinary iodine to return to its baseline value after the use of water-soluble iodinated contrast agents in post-thyroidectomy patients requiring radioiodine therapy. Thyroid. 2012; 22:926–930
Sohn SY, Choi JH, Kim NK, Joung JY, Cho YY, Park SM, et al. The impact of iodinated contrast agent administered during preoperative computed tomography scan on body iodine pool in patients with differentiated thyroid cancer preparing for radioactive iodine treatment. Thyroid. 2014; 24:872–877
Higashi T, Nishii R, Yamada S, Nakamoto Y, Ishizu K, Kawase S, et al. Delayed initial radioactive iodine therapy resulted in poor survival in patients with metastatic differentiated thyroid carcinoma: a retrospective statistical analysis of 198 cases. J Nucl Med. 2011; 52:683–689

Auteurs

Justin D Rodriguez (JD)

Division of Nuclear Medicine, Department of Radiology.

Deepa Kirk (D)

Division of Endocrinology, Department of Medicine.

Thad Benefield (T)

Division of Nuclear Medicine, Department of Radiology.

Susan J Maygarden (SJ)

Department of Pathology.

Karla Pou (K)

Division of Surgical Oncology, Department of Surgery.

Lawrence T Kim (LT)

Division of Surgical Oncology, Department of Surgery.

Trevor G Hackman (TG)

Department of Otolaryngology/Head and Neck Surgery, UNC School of Medicine, Chapel Hill, North Carolina, USA.

Amir H Khandani (AH)

Division of Nuclear Medicine, Department of Radiology.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH