Primary mesenchymal chondrosarcoma of the kidney without
HEY1-NCOA2 fusion
IRF2BP2-CDX1 fusion
mesenchymal chondrosarcoma
tumor thrombus
Journal
Oncology letters
ISSN: 1792-1074
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
19
06
2019
accepted:
08
10
2019
entrez:
4
1
2020
pubmed:
4
1
2020
medline:
4
1
2020
Statut:
ppublish
Résumé
Mesenchymal chondrosarcoma (MC) of the kidney is rare. To the best of our knowledge, the current report is the first case of a giant extraskeletal MC that arose primarily from the right kidney and mimicked renal cell carcinoma at the locally advanced stage (cT3bN0) with vena cava thrombus and multiple pulmonary arterial tumor emboli. Additionally, the literature on renal EMC is reviewed and the possibilities of oncogenic heterogeneity are discussed. A 64-year-old woman was admitted to Yamagata University Hospital for sudden onset of asymptomatic gross hematuria. CT revealed a 90 mm renal mass without calcification in the right kidney and tumor thrombus extending to the inferior vena cava. Radical nephrectomy with thrombectomy was performed. Lung metastasis was detected 2 months later. The patient received systemic chemotherapy, which was only marginally effective. She died of the malignancy 8 months after surgery. Microscopic examination of the tumor revealed typical histology of MC and a lack of
Identifiants
pubmed: 31897203
doi: 10.3892/ol.2019.11143
pii: OL-0-0-11143
pmc: PMC6924144
doi:
Types de publication
Journal Article
Langues
eng
Pagination
885-891Informations de copyright
Copyright: © Yamagishi et al.
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