The prognostic value of tumor mutation burden in
Lung adenocarcinoma (LUAD)
epidermal growth factor receptor mutation (EGFR mutation)
overall survival (OS)
prognosis
tumor mutation burden (TMB)
Journal
Journal of thoracic disease
ISSN: 2072-1439
Titre abrégé: J Thorac Dis
Pays: China
ID NLM: 101533916
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
entrez:
7
1
2020
pubmed:
7
1
2020
medline:
7
1
2020
Statut:
ppublish
Résumé
Tumor mutation burden (TMB) is novel biomarker of promising predict value in prediction of immune checkpoint inhibitors (ICPis) in non-small cell lung cancer (NSCLC). However, the distribution of TMB in epidermal growth factor receptor ( Information regarding gene mutations and patients' survival time in advanced LUAD was downloaded from The Cancer Genome Atlas (TCGA) database. The diversity of TMB in different The median TMB values of In advanced LUAD patients, TMB was lower in patients with
Sections du résumé
BACKGROUND
BACKGROUND
Tumor mutation burden (TMB) is novel biomarker of promising predict value in prediction of immune checkpoint inhibitors (ICPis) in non-small cell lung cancer (NSCLC). However, the distribution of TMB in epidermal growth factor receptor (
METHODS
METHODS
Information regarding gene mutations and patients' survival time in advanced LUAD was downloaded from The Cancer Genome Atlas (TCGA) database. The diversity of TMB in different
RESULTS
RESULTS
The median TMB values of
CONCLUSIONS
CONCLUSIONS
In advanced LUAD patients, TMB was lower in patients with
Identifiants
pubmed: 31903239
doi: 10.21037/jtd.2019.11.04
pii: jtd-11-11-4507
pmc: PMC6940222
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4507-4515Informations de copyright
2019 Journal of Thoracic Disease. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: The authors have no conflicts of interest to declare.
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