[Antibodies, tools of choice for fluorescence-guided surgery].
Les anticorps, outils de choix pour la chirurgie guidée par fluorescence.
Journal
Medecine sciences : M/S
ISSN: 1958-5381
Titre abrégé: Med Sci (Paris)
Pays: France
ID NLM: 8710980
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
entrez:
7
1
2020
pubmed:
7
1
2020
medline:
23
6
2020
Statut:
ppublish
Résumé
Fluorescence-guided surgery has been developing in clinics for several years. While the use of non-targeted dyes may be useful in certain diseases, specific contrast agents are essential in oncology. As shown in the latest clinical studies, monoclonal antibodies have all the characteristics to play a major role in this field of medical imaging, provided the antigenic target is relevant. Les anticorps, outils de choix pour la chirurgie guidée par fluorescence. La chirurgie guidée par fluorescence se développe en clinique depuis plusieurs années. Si l’utilisation de colorants non ciblés peut être utile dans certaines pathologies, des agents de contraste spécifiques sont indispensables en oncologie. Comme le montrent les dernières études cliniques, les anticorps monoclonaux ont toutes les caractéristiques pour jouer un rôle majeur dans ce domaine d’imagerie médicale, à condition que la cible antigénique soit pertinente.
Autres résumés
Type: Publisher
(fre)
Les anticorps, outils de choix pour la chirurgie guidée par fluorescence.
Identifiants
pubmed: 31903919
doi: 10.1051/medsci/2019207
pii: msc190230
doi:
Substances chimiques
Antibodies, Monoclonal
0
Contrast Media
0
Fluorescent Dyes
0
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
1066-1071Informations de copyright
© 2019 médecine/sciences – Inserm.
Références
Wong LS, McMahon J, Devine J, et al. Influence of close resection margins on local recurrence and disease-specific survival in oral and oropharyngeal carcinoma. Br J Oral Maxillofac Surg 2012 ; 50: 102–108.
Vos EL, Gaal J, Verhoef C, et al. Focally positive margins in breast conserving surgery: predictors, residual disease, and local recurrence. Eur J Surg Oncol 2017 ; 43: 1846–1854.
Vahrmeijer AL, Hutteman M, van der Vorst JR, et al. Image-guided cancer surgery using near-infrared fluorescence. Nat Rev Clin Oncol 2013 ; 10: 507–518.
Nguyen QT, Tsien RY. Fluorescence-guided surgery with live molecular navigation: a new cutting edge. Nat Rev Cancer 2013 ; 13: 653–662.
Rosenthal EL, Warram JM, de Boer E, et al. Successful translation of fluorescence navigation during oncologic surgery: a consensus report. J Nucl Med 2016 ; 57: 144–150.
Gioux S, Choi HS, Frangioni JV. Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation. Mol Imaging 2010 ; 9: 237–255.
Keereweer S, Van Driel PBAA, Snoeks TJA, et al. Optical image-guided cancer surgery: challenges and limitations. Clin Cancer Res 2013 ; 19: 3745–3754.
DSouza AV, Lin H, Henderson ER, et al. Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging. J Biomed Opt 2016; 21: 80901.
van Dam GM, Themelis G, Crane LMA, et al. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med 2011 ; 17: 1315–1319.
Reinhart MB, Huntington CR, Blair LJ, et al. Indocyanine green: historical context, current applications, and future considerations. Surg Innov 2016 ; 23: 166–175.
Debie P, Hernot S. Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making. Front Pharmacol 2019 ; 10: 510.
Hernot S, van Manen L, Debie P, et al. Latest developments in molecular tracers for fluorescence image-guided cancer surgery. Lancet Oncol 2019 ; 20: e354–e367.
Liberale G, Bourgeois P, Larsimont D, et al. Indocyanine green fluorescence-guided surgery after IV injection in metastatic colorectal cancer: a systematic review. Eur J Surg Oncol 2017 ; 43: 1656–1667.
Mochida A, Ogata F, Nagaya T, et al. Activatable fluorescent probes in fluorescence-guided surgery: practical considerations. Bioorg Med Chem 2018 ; 26: 925–930.
Pèlegrin A, Folli S, Buchegger F, et al. Antibody-fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice. Cancer 1991 ; 67: 2529–2537.
Folli S, Westermann P, Braichotte D, et al. Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice. Cancer Res 1994 ; 54: 2643–2649.
Folli S, Wagnières G, Pèlegrin A, et al. Immunophotodiagnosis of colon carcinomas in patients injected with fluoresceinated chimeric antibodies against carcinoembryonic antigen. Proc Natl Acad Sci USA 1992 ; 89: 7973–7977.
Korb ML, Hartman YE, Kovar J, et al. Use of monoclonal antibody-IRDye800CW bioconjugates in the resection of breast cancer. J Surg Res 2014 ; 188: 119–128.
Boonstra MC, Tolner B, Schaafsma BE, et al. Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors. Int J Cancer 2015 ; 137: 1910–1920.
Metildi CA, Kaushal S, Snyder CS, et al. Fluorescence-guided surgery of human colon cancer increases complete resection resulting in cures in an orthotopic nude mouse model. J Surg Res 2013 ; 179: 87–93.
Metildi CA, Kaushal S, Pu M, et al. Fluorescence-guided surgery with a fluorophore-conjugated antibody to carcinoembryonic antigen (CEA), that highlights the tumor, improves surgical resection and increases survival in orthotopic mouse models of human pancreatic cancer. Ann Surg Oncol 2014 ; 21: 1405–1411.
Tipirneni KE, Warram JM, Moore LS, et al. Oncologic procedures amenable to fluorescence-guided surgery. Ann Surg 2017 ; 266: 36–47.
Cohen R, Stammes MA, de Roos IH, et al. Inert coupling of IRDye800CW to monoclonal antibodies for clinical optical imaging of tumor targets. EJNMMI Res 2011 ; 1: 31.
Harlaar NJ, Koller M, de Jongh SJ, et al. Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study. Lancet Gastroenterol Hepatol 2016 ; 1: 283–290.
Lamberts LE, Koch M, de Jong JS, et al. Tumor-specific uptake of fluorescent bevacizumab-IRDye800CW microdosing in patients with primary breast cancer: a Phase I feasibility study. Clin Cancer Res 2017 ; 23: 2730–2741.
de Boer E, Warram JM, Tucker MD, et al. In vivo fluorescence immunohistochemistry: localization of fluorescently labeled cetuximab in squamous cell carcinomas. Sci Rep 2015 ; 5: 10169.
Rosenthal EL, Warram JM, de Boer E, et al. Safety and tumor specificity of cetuximab-IRDye800 for surgical navigation in head and neck cancer. Clin Cancer Res 2015 ; 21: 3658–3666.
Rosenthal EL, Moore LS, Tipirneni K, et al. Sensitivity and specificity of cetuximab-IRDye800CW to identify regional metastatic disease in head and neck cancer. Clin Cancer Res 2017 ; 23: 4744–4752.
Gao RW, Teraphongphom N, de Boer E, et al. Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers. Theranostics 2018 ; 8: 2488–2495.
Tummers WS, Miller SE, Teraphongphom NT, et al. Intraoperative pancreatic cancer detection using tumor-specific multimodality molecular imaging. Ann Surg Oncol 2018 ; 25: 1880–1888.
Tummers WS, Miller SE, Teraphongphom NT, et al. Detection of visually occult metastatic lymph nodes using molecularly targeted fluorescent imaging during surgical resection of pancreatic cancer. HPB (Oxford) 2019 ; 21: 883–890.
Miller SE, Tummers WS, Teraphongphom N, et al. First-in-human intraoperative near-infrared fluorescence imaging of glioblastoma using cetuximab-IRDye800. J Neurooncol 2018 ; 139: 135–143.
van Keulen S, van den Berg NS, Nishio N, et al. Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma. Oral Oncol 2019 ; 88: 58–65.
van Keulen S, Nishio N, Fakurnejad S, et al. The clinical application of fluorescence-guided surgery in head and neck cancer. J Nucl Med 2019 ; 60: 758–763.
Gao RW, Teraphongphom NT, van den Berg NS, et al. Determination of tumor margins with surgical specimen mapping using near-infrared fluorescence. Cancer Res 2018 ; 78: 5144–5154.
Boogerd LSF, Vuijk FA, Hoogstins CES, et al. Correlation between preoperative serum carcinoembryonic antigen levels and expression on pancreatic and rectal cancer tissue. Biomark Cancer 2017; 9: 1179299X17710016.
Gutowski M, Framery B, Boonstra MC, et al. SGM-101: an innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery. Surg Oncol 2017 ; 26: 153–162.
Boogerd LSF, Hoogstins CES, Schaap DP, et al. Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study. Lancet Gastroenterol Hepatol 2018 ; 3: 181–191.
Hoogstins CES, Boogerd LSF, Sibinga Mulder BG, et al. Image-guided surgery in patients with pancreatic cancer: First results of a clinical trial using SGM-101, a novel carcinoembryonic antigen-targeting, near-infrared fluorescent agent. Ann Surg Oncol 2018 ; 25: 3350–3357.
Boonstra MC, de Geus SWL, Prevoo HAJM, et al. Selecting targets for tumor imaging: an overview of cancer-associated membrane proteins. Biomark Cancer 2016 ; 8: 119–133.
Frangioni JV. New technologies for human cancer imaging. J Clin Oncol 2008 ; 26: 4012–4021.
Boni L, David G, Mangano A, et al. Clinical applications of indocyanine green (ICG) enhanced fluorescence in laparoscopic surgery. Surg Endosc 2015 ; 29: 2046–2055.
Owens EA, Henary M, El Fakhri G, et al. Tissue-specific near-infrared fluorescence imaging. Acc Chem Res 2016 ; 49: 1731–1740.
Ortega C, Herbet A, Richard S, et al. High level prokaryotic expression of anti-Müllerian inhibiting substance type II receptor diabody, a new recombinant antibody for in vivo ovarian cancer imaging. J Immunol Methods 2012 ; 387: 11–20.
van Driel PBAA, van der Vorst JR, Verbeek FPR, et al. Intraoperative fluorescence delineation of head and neck cancer with a fluorescent anti-epidermal growth factor receptor nanobody. Int J Cancer 2014 ; 134: 2663–2673.
Krüwel T, Nevoltris D, Bode J, et al. In vivo detection of small tumour lesions by multi-pinhole SPECT applying a (99m)Tc-labelled nanobody targeting the epidermal growth factor receptor. Sci Rep 2016 ; 6: 21834.
Sato K, Gorka AP, Nagaya T, et al. Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates. Mol Biosyst 2016 ; 12: 3046–3056.
Urano Y, Sakabe M, Kosaka N, et al. Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe. Sci Transl Med 2011; 3: 110ra119.
Cuesta AM, Sainz-Pastor N, Bonet J, et al. Multivalent antibodies: when design surpasses evolution. Trends Biotechnol 2010 ; 28: 355–362.
Tummers WS, Warram JM, Tipirneni KE, et al. Regulatory aspects of optical methods and exogenous targets for cancer detection. Cancer Res 2017 ; 77: 2197–2206.
Beck A, Dumontet C, Joubert N. Les immunoconjugués en oncologie: les raisons du succès récent d’une approche ancienne. Med Sci (Paris) 2019 ; 35: 1034–1042.
Beck A, Dumontet C, Joubert N. Les immunoconjugués en oncologie: les nouvelles stratégies en développement. Med Sci (Paris) 2019 ; 35: 1043–1053.