Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.

Chemistry, Pharmaceutical Drug Discovery Humans

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
28 Dec 2019
Historique:
received: 24 12 2019
accepted: 24 12 2019
entrez: 8 1 2020
pubmed: 8 1 2020
medline: 29 5 2020
Statut: epublish

Résumé

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials that is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal

Identifiants

DOI: 10.3390/molecules25010119 PMID: 31905602 PMC: PMC6983133
pubmed: 31905602
pii: molecules25010119
doi: 10.3390/molecules25010119
pmc: PMC6983133
pii:
doi:

Types de publication

Editorial

Langues

eng

Sous-ensembles de citation

IM

Références

J Med Chem. 2018 Jun 28;61(12):5412-5423
pubmed: 29877709
Chem Rev. 2016 Jan 27;116(2):719-66
pubmed: 26751274
Antimicrob Agents Chemother. 2014;58(1):325-32
pubmed: 24165182
J Med Chem. 2020 Mar 12;63(5):2325-2342
pubmed: 31689108
Annu Rev Microbiol. 2010;64:43-60
pubmed: 20420522
Front Microbiol. 2016 Sep 21;7:1483
pubmed: 27708632
Nat Rev Microbiol. 2003 Oct;1(1):17-24
pubmed: 15040176
Nat Commun. 2019 Aug 14;10(1):3673
pubmed: 31413254
Cell Res. 2019 Oct;29(10):787-803
pubmed: 31488882
JAMA. 1994 Apr 6;271(13):992-8
pubmed: 8139084
Sci Transl Med. 2019 Sep 25;11(511):
pubmed: 31554736
J Med Chem. 2019 Nov 27;62(22):10062-10097
pubmed: 31487175
J Am Chem Soc. 2019 Nov 20;141(46):18421-18427
pubmed: 31584808
Nat Chem. 2020 Jan;12(1):26-35
pubmed: 31767992
J Med Chem. 2019 Nov 14;62(21):9375-9414
pubmed: 31050421
Molecules. 2019 Oct 25;24(21):
pubmed: 31731542
Eur J Med Chem. 2019 Dec 1;183:111701
pubmed: 31550662
Gastroenterology. 2019 Oct;157(4):1019-1031.e7
pubmed: 31279870
Int J Mol Sci. 2019 Apr 18;20(8):
pubmed: 31003542
Nat Chem. 2019 Dec;11(12):1113-1123
pubmed: 31659311
J Med Chem. 2017 Jun 8;60(11):4573-4576
pubmed: 28453272
J Med Chem. 2019 Oct 24;62(20):8953-8972
pubmed: 31314518
N Engl J Med. 2016 Nov 17;375(20):1946-1960
pubmed: 27959607
J Med Chem. 2019 Oct 24;62(20):8973-8995
pubmed: 31318208
Pharmaceuticals (Basel). 2019 Oct 23;12(4):
pubmed: 31652873
J Med Chem. 2019 Oct 24;62(20):9078-9102
pubmed: 31609608
Mol Cancer Ther. 2019 Aug;18(8):1386-1395
pubmed: 31092563
ACS Infect Dis. 2019 Jul 12;5(7):1105-1114
pubmed: 31012301
Mol Cancer Ther. 2020 Jan;19(1):75-88
pubmed: 31554654
Br J Pharmacol. 2020 Jan;177(2):267-281
pubmed: 31499592
Nanoscale. 2019 Sep 7;11(33):15479-15486
pubmed: 31237302
Nat Commun. 2019 Nov 19;10(1):5221
pubmed: 31745082
Drug Discov Today. 2018 Mar;23(3):605-615
pubmed: 29330127
J Med Chem. 2020 Feb 13;63(3):944-960
pubmed: 31755711
Oncotarget. 2016 Jan 5;7(1):593-609
pubmed: 26573230
J Antimicrob Chemother. 2020 Feb 1;75(2):409-417
pubmed: 31642901
Sci Transl Med. 2019 Sep 11;11(509):
pubmed: 31511426
Nat Cell Biol. 2019 Nov;21(11):1425-1435
pubmed: 31685994
Nat Rev Drug Discov. 2019 Jan;18(1):41-58
pubmed: 30310233
Commun Biol. 2019 Sep 17;2:345
pubmed: 31552298
J Med Chem. 2019 Dec 12;62(23):10617-10629
pubmed: 31714776
J Med Chem. 2019 Dec 12;62(23):10586-10604
pubmed: 31517489
Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):3-26
pubmed: 11259830
J Med Chem. 2020 Jan 9;63(1):321-333
pubmed: 31794211
Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22353-22358
pubmed: 31611414
Nat Commun. 2019 Nov 1;10(1):5015
pubmed: 31676778
Alzheimers Dement (N Y). 2019 Jul 09;5:272-293
pubmed: 31334330
Nat Chem. 2019 Nov;11(11):1041-1048
pubmed: 31548671
Am J Respir Cell Mol Biol. 2017 Sep;57(3):270-271
pubmed: 28862508
Molecules. 2019 Nov 20;24(23):
pubmed: 31756986
Mol Pharm. 2019 Oct 7;16(10):4292-4301
pubmed: 31503493
J Med Chem. 2019 Nov 14;62(21):9718-9731
pubmed: 31626545
J Med Chem. 2020 Jan 23;63(2):542-568
pubmed: 31756109
Nat Med. 2014 Apr;20(4):385-397
pubmed: 24633305
ACS Med Chem Lett. 2019 Jul 10;10(8):1216-1221
pubmed: 31413808
Eur J Med Chem. 2019 Dec 15;184:111735
pubmed: 31610378
Molecules. 2019 Oct 16;24(20):
pubmed: 31623252
J Med Chem. 2019 Nov 14;62(21):9824-9836
pubmed: 31603678
Cell. 2017 Jan 26;168(3):527-541.e29
pubmed: 28111073
Biochem Biophys Res Commun. 2011 May 27;409(1):14-21
pubmed: 21549094
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1615-1622
pubmed: 31480869
Med Res Rev. 2018 Sep;38(6):1799-1836
pubmed: 29635752
J Med Chem. 2019 Nov 14;62(21):9732-9742
pubmed: 31603323
Nat Rev Drug Discov. 2017 Mar;16(3):181-202
pubmed: 27807347
Am J Respir Crit Care Med. 1996 Jun;153(6 Pt 1):1802-11
pubmed: 8665038
Nature. 2019 Dec;576(7787):459-464
pubmed: 31747680
J Med Chem. 2019 Dec 12;62(23):10676-10690
pubmed: 31715099

Auteurs

Jean Jacques Vanden Eynde (JJ)

Formerly head of the Department of Organic Chemistry (FS), University of Mons-UMONS, 7000 Mons, Belgium.
ORCID: 0000-0003-4770-4104

Arduino A Mangoni (AA)

Discipline of Clinical Pharmacology, College of Medicine and Public Health, Flinders University and Flinders Medical Centre, Bedford Park 5042, Adelaide, Australia.
Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01069 Dresden, Germany.
ORCID: 0000-0001-8699-1412

Jarkko Rautio (J)

School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.

Jérôme Leprince (J)

UNIROUEN, Inserm U1239, Laboratory of Neuronal and Neuroendocrine Communication and Differentiation, Normandie University, 76000 Rouen, France.
UNIROUEN, Regional Cell Imaging Platform of Normandy (PRIMACEN), Normandie University, 76000 Rouen, France.
ORCID: 0000-0002-7814-9927

Yasu-Taka Azuma (YT)

Laboratory of Veterinary Pharmacology, Division of Veterinary Science, Osaka Prefecture University Graduate School of Life and Environmental Sciences, 1-58 Rinku-ohraikita, Izumisano, Osaka 598-8531, Japan.

Alfonso T García-Sosa (AT)

Institute of Chemistry, University of Tartu, Ravila 14a, 50411 Tartu, Estonia.
ORCID: 0000-0003-0542-4446

Christopher Hulme (C)

Department of Pharmacology and Toxicology, and Department of Chemistry and Biochemistry, College of Pharmacy, The University of Arizona, Biological Sciences West Room 351, 1041 East Lowell Street, Tucson, AZ 85721, USA.

Josef Jampilek (J)

Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 842 15 Bratislava, Slovakia.
ORCID: 0000-0003-2003-9052

Rafik Karaman (R)

Pharmaceutical & Medicinal Chemistry Department, Faculty of Pharmacy, Al-Quds University, Jerusalem P.O. Box 20002, Palestine.
Department of Sciences, University of Basilicata, Viadell'Ateneo Lucano 10, 85100 Potenza, Italy.
ORCID: 0000-0001-5526-4490

Wei Li (W)

Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
ORCID: 0000-0002-9522-4474

Paula A C Gomes (PAC)

LAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
ORCID: 0000-0002-6018-4724

Dimitra Hadjipavlou-Litina (D)

Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
ORCID: 0000-0002-1844-350X

Raffaele Capasso (R)

Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici (NA), Italy.
ORCID: 0000-0002-3335-1822

Athina Geronikaki (A)

School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

Laura Cerchia (L)

Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), 80131 Naples, Italy.
ORCID: 0000-0002-7633-7932

Jean-Marc Sabatier (JM)

Institute of NeuroPhysiopathology, UMR 7051, Faculté de Médecine Secteur Nord, 51, Boulevard Pierre Dramard-CS80011, 13344-Marseille CEDEX 15, France.
ORCID: 0000-0002-9040-5647

Rino Ragno (R)

Rome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.
ORCID: 0000-0001-5399-975X

Tiziano Tuccinardi (T)

Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
ORCID: 0000-0002-6205-4069

Andrea Trabocchi (A)

Department of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 13, I-50019 Sesto Fiorentino, Florence, Italy.
ORCID: 0000-0003-1774-9301

Jean-Yves Winum (JY)

Institut des Biomolécules Max Mousseron (IBMM), École nationale supérieure de chimie de Montpellier (ENSCM), Université de Montpellier, CEDEX 05, 34296 Montpellier, France.
ORCID: 0000-0003-3197-3414

F Javier Luque (FJ)

Department of Nutrition, Food Sciences and Gastronomy, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB) and Institute of Theoretical and Computational Chemistry (IQTC), University of Barcelona, Av. Prat de la Riba 171, E-08921 Santa Coloma de Gramenet, Spain.
ORCID: 0000-0002-8049-3567

Katalin Prokai-Tatrai (K)

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA.
ORCID: 0000-0001-5595-1346

Mariana Spetea (M)

Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, 6020 Innsbruck, Austria.
ORCID: 0000-0002-2379-5358

Michael Gütschow (M)

Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53115 Bonn, Germany.
ORCID: 0000-0002-9376-7897

Ivan Kosalec (I)

Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia.
ORCID: 0000-0002-3010-1537

Catherine Guillou (C)

Institut de Chimie des Substances Naturelles, CNRS UPR 2301, Unversité de Paris-Saclay, 1 av. de la Terrasse, 91198 Gif-sur-Yvette, France.
ORCID: 0000-0003-0693-0703

M Helena Vasconcelos (MH)

i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal.
Cancer Drug Resistance Group-IPATIMUP-Institute of Molecular Pathology and Immunology of the University of Porto, Rua Júlio Amaral de Carvalho, 45, 4200-135 Porto, Portugal.
Department of Biological Sciences, FFUP-Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
ORCID: 0000-0002-7801-4643

George Kokotos (G)

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, 15771 Athens, Greece.
ORCID: 0000-0003-3753-7082

Giulio Rastelli (G)

Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103, 41125 Modena, Italy.
ORCID: 0000-0002-2474-0607

Maria Emília de Sousa (ME)

Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências, Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), Universidade do Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N 4450-208 Matosinhos, Portugal.
ORCID: 0000-0002-5397-4672

Clementina Manera (C)

Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
ORCID: 0000-0002-7379-5743

Sandra Gemma (S)

Department of Biotechnology, Chemistry and Pharmacy, DoE 2018-2022, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.
ORCID: 0000-0002-8313-2417

Stefano Mangani (S)

Department of Biotechnology, Chemistry and Pharmacy, DoE 2018-2022, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.
ORCID: 0000-0003-4824-7478

Carlo Siciliano (C)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036 Arcavacata di Rende, Italy.
ORCID: 0000-0002-0584-219X

Stefania Galdiero (S)

Department of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.
ORCID: 0000-0002-7849-7024

Hong Liu (H)

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.

Peter J H Scott (PJH)

Department of Radiology, University of Michigan, Ann Arbor, MI 48105, USA.
ORCID: 0000-0002-6505-0450

Cristóbal de Los Ríos (C)

Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de la Princesa, 28006 Madrid, Spain.
ORCID: 0000-0002-6456-7589

Luigi A Agrofoglio (LA)

ICOA, CNRS UMR 7311, Université d'Orleans, Rue de Chartres, 45067 Orleans CEDEX 2, France.
ORCID: 0000-0002-6083-0810

Simona Collina (S)

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
ORCID: 0000-0002-2954-7558

Rita C Guedes (RC)

iMed.Ulisboa and Faculdade de Farmácia, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
ORCID: 0000-0002-5790-9181

Diego Muñoz-Torrero (D)

Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII, 27-31, E-08028 Barcelona, Spain.
ORCID: 0000-0002-8140-8555

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Classifications MeSH

questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Chimie pharmaceutique › Breakthroughs in Medicinal Chemistry: New...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Breakthroughs in Medicinal Chemistry: New...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Breakthroughs in Medicinal Chemistry: New...