HIV-1 Mutant Assembly, Processing and Infectivity Expresses Pol Independent of Gag.

Cysteine Endopeptidases / genetics Fusion Proteins, gag-pol / genetics Gene Expression Regulation, Viral HEK293 Cells HIV Protease / genetics HIV Reverse Transcriptase / genetics HIV-1 / genetics HeLa Cells Humans Viral Load Virion / metabolism Virus Assembly Virus Replication gag Gene Products, Human Immunodeficiency Virus / genetics pol Gene Products, Human Immunodeficiency Virus / genetics
Gag Gag–Pol HIV-1 Pol virus assembly virus processing

Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
02 01 2020
Historique:
received: 28 11 2019
revised: 30 12 2019
accepted: 30 12 2019
entrez: 8 1 2020
pubmed: 8 1 2020
medline: 7 2 2021
Statut: epublish

Résumé

The

Identifiants

DOI: 10.3390/v12010054 PMID: 31906562 PMC: PMC7019881
pubmed: 31906562
pii: v12010054
doi: 10.3390/v12010054
pmc: PMC7019881
pii:
doi:

Substances chimiques

Fusion Proteins, gag-pol 0
gag Gene Products, Human Immunodeficiency Virus 0
pol Gene Products, Human Immunodeficiency Virus 0
reverse transcriptase, Human immunodeficiency virus 1 EC 2.7.7.-
HIV Reverse Transcriptase EC 2.7.7.49
Cysteine Endopeptidases EC 3.4.22.-
HIV Protease EC 3.4.23.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Références

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Auteurs

Fu-Hsien Yu (FH)

Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.

Kuo-Jung Huang (KJ)

Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.

Chin-Tien Wang (CT)

Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei 112, Taiwan.
Department of Medical Research, Taipei Veterans General Hospital, Taipei 112, Taiwan.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Endopeptidases › Cysteine endopeptidases › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › Protéines du core viral › Produits du gène pol › Protéines de fusion gag-pol › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes viraux › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales non structurales › Protéases virales › Protéase du VIH › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › Protéines du core viral › Produits du gène pol › RNA-directed DNA polymerase › Transcriptase inverse du VIH › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Virus › Virus à ARN › Retroviridae › Lentivirus › Lentivirus des primates › VIH (Virus de l'Immunodéficience Humaine) › VIH-1 (Virus de l'Immunodéficience Humaine de type 1) › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HeLa › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Charge virale › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Structures virales › Virion › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › Assemblage viral › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Phénomènes microbiologiques › Phénomènes physiologiques viraux › Réplication virale › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › Protéines du core viral › Produits du gène gag › Produits du gène gag du virus de l'immunodéficience humaine › HIV-1 Mutant Assembly, Processing and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines virales › Protéines virales structurales › Protéines nucléocapside › Protéines du core viral › Produits du gène pol › Produits du gène pol du virus de l'immunodéficience humaine › HIV-1 Mutant Assembly, Processing and...