Pathogens Causing Respiratory Tract Infections in Children Less Than 5 Years of Age in Senegal.
Acute respiratory tract infection
case-control study
cause
child
low- and middle-income country
Journal
Microbiology insights
ISSN: 1178-6361
Titre abrégé: Microbiol Insights
Pays: United States
ID NLM: 101622216
Informations de publication
Date de publication:
2019
2019
Historique:
received:
10
09
2019
accepted:
03
11
2019
entrez:
8
1
2020
pubmed:
8
1
2020
medline:
8
1
2020
Statut:
epublish
Résumé
While acute respiratory tract infections are the main cause of paediatric mortality and morbidity worldwide, pathogen patterns shift due to factors such as hygiene, vaccinations, and antibiotic resistance. Knowledge about current cause of respiratory infections is lacking, particularly in low- and middle-income countries. The aim of this study was to identity the various respiratory pathogens causing acute respiratory tract infections in children below 5 years of age visiting a sub-urban primary care clinic in Senegal. A case-control study was performed in September and October 2018. Oropharyngeal swabs were collected from cases; infants with fever and respiratory symptoms, and controls; children involved in the vaccination programme. Viral identification was conducted by polymerase chain reaction for 21 different viruses; bacteria were identified by culture studies. Associations between microorganisms, acute respiratory infection and severity of disease were calculated by multivariate regression adjusting for confounders such as age, sex, and living area. Overall, 102 cases and 96 controls were included. Microorganisms were detected in 90.1% of cases and 53.7% of controls ( This case-control study in a primary care setting in sub-Saharan Africa found influenza virus A and B, RSV, and
Identifiants
pubmed: 31908474
doi: 10.1177/1178636119890885
pii: 10.1177_1178636119890885
pmc: PMC6937528
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1178636119890885Informations de copyright
© The Author(s) 2019.
Déclaration de conflit d'intérêts
Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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