Which one came first: movement behavior or frailty? A cross-lagged panel model in the Toledo Study for Healthy Aging.
Ageing
Exercise
Functioning and disability
Longitudinal
Sedentary time
Structural equation modelling
Journal
Journal of cachexia, sarcopenia and muscle
ISSN: 2190-6009
Titre abrégé: J Cachexia Sarcopenia Muscle
Pays: Germany
ID NLM: 101552883
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
30
05
2019
revised:
05
08
2019
accepted:
25
09
2019
pubmed:
9
1
2020
medline:
7
7
2021
entrez:
9
1
2020
Statut:
ppublish
Résumé
There has been limited longitudinal assessment of the relationship between moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) with frailty, and no studies have explored the possibility of reverse causality. This study aimed to determine the potential bidirectionality of the relationship between accelerometer-assessed MVPA, SB, and frailty over time in older adults. Participants were from the Toledo Study for Healthy Aging. We analysed 186 older people aged 67 to 90 (76.7 ± 3.9; 52.7% female participants) over a 4-year period. Time spent in SB and MVPA was assessed by accelerometry. Frailty Trait Scale was used to determine frailty levels. A cross-lagged panel model design was used to test the reciprocal relationships between MVPA/SB and frailty. Frailty Trait Scale score changed from 35.4 to 43.8 points between the two times (P < 0.05). We also found a reduction of 7 min/day in the time spent on MVPA (P < 0.05), and participants tended to spend more time on SB (P = 0.076). Our analyses revealed that lower levels of initial MVPA predicted higher levels of later frailty [std. β = -0.126; confidence interval (CI) = -0.231, -0.021; P < 0.05], whereas initial spent time on SB did not predict later frailty (std. β = -0.049; CI = -0.185, 0.087; P = 0.48). Conversely, an initial increased frailty status predicted higher levels of later SB (std. β = 0.167; CI = 0.026, 0.307; P < 0.05) but not those of MVPA (std. β = 0.071; CI = -0.033, 0.175; P = 0.18). Our observations suggest that the relationship between MVPA/SB and frailty is unidirectional: individuals who spent less time on MVPA at baseline are more likely to increase their frailty score, and individuals who are more frail are more likely to spent more time on SB at follow-up. Interventions and policies should aim to increase MVPA levels from earlier stages to promote successful aging.
Sections du résumé
BACKGROUND
There has been limited longitudinal assessment of the relationship between moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) with frailty, and no studies have explored the possibility of reverse causality. This study aimed to determine the potential bidirectionality of the relationship between accelerometer-assessed MVPA, SB, and frailty over time in older adults.
METHODS
Participants were from the Toledo Study for Healthy Aging. We analysed 186 older people aged 67 to 90 (76.7 ± 3.9; 52.7% female participants) over a 4-year period. Time spent in SB and MVPA was assessed by accelerometry. Frailty Trait Scale was used to determine frailty levels. A cross-lagged panel model design was used to test the reciprocal relationships between MVPA/SB and frailty.
RESULTS
Frailty Trait Scale score changed from 35.4 to 43.8 points between the two times (P < 0.05). We also found a reduction of 7 min/day in the time spent on MVPA (P < 0.05), and participants tended to spend more time on SB (P = 0.076). Our analyses revealed that lower levels of initial MVPA predicted higher levels of later frailty [std. β = -0.126; confidence interval (CI) = -0.231, -0.021; P < 0.05], whereas initial spent time on SB did not predict later frailty (std. β = -0.049; CI = -0.185, 0.087; P = 0.48). Conversely, an initial increased frailty status predicted higher levels of later SB (std. β = 0.167; CI = 0.026, 0.307; P < 0.05) but not those of MVPA (std. β = 0.071; CI = -0.033, 0.175; P = 0.18).
CONCLUSIONS
Our observations suggest that the relationship between MVPA/SB and frailty is unidirectional: individuals who spent less time on MVPA at baseline are more likely to increase their frailty score, and individuals who are more frail are more likely to spent more time on SB at follow-up. Interventions and policies should aim to increase MVPA levels from earlier stages to promote successful aging.
Identifiants
pubmed: 31912990
doi: 10.1002/jcsm.12511
pmc: PMC7113532
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
415-423Informations de copyright
© 2020 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders.
Références
Lancet. 2013 Mar 2;381(9868):752-62
pubmed: 23395245
J Gerontol A Biol Sci Med Sci. 2014 Jan;69(1):73-8
pubmed: 23640762
J Cachexia Sarcopenia Muscle. 2015 Dec;6(4):278-86
pubmed: 26675566
J Am Med Dir Assoc. 2016 Dec 1;17(12):1163.e1-1163.e17
pubmed: 27886869
Int J Obes (Lond). 2017 Sep;41(9):1361-1368
pubmed: 28529332
PLoS One. 2017 Feb 2;12(2):e0170878
pubmed: 28152084
Eur J Sport Sci. 2017 Aug;17(7):940-953
pubmed: 28532299
J Abnorm Psychol. 2003 Nov;112(4):545-57
pubmed: 14674868
Maturitas. 2014 Sep;79(1):91-5
pubmed: 25022468
Int J Epidemiol. 2017 Feb 1;46(1):141-148
pubmed: 27209633
J Am Med Dir Assoc. 2012 Jul;13(6):507-11
pubmed: 22572554
Eur Heart J. 2006 Aug;27(15):1861-7
pubmed: 16820367
Cold Spring Harb Perspect Med. 2016 Jun 01;6(6):
pubmed: 27143701
CMAJ. 2005 Aug 30;173(5):489-95
pubmed: 16129869
Int J Behav Nutr Phys Act. 2017 Apr 26;14(1):54
pubmed: 28446189
Br J Sports Med. 2017 Nov;51(21):1526-1532
pubmed: 28724710
PLoS One. 2018 Oct 22;13(10):e0206013
pubmed: 30346973
J Nutr Health Aging. 2011 Dec;15(10):852-6
pubmed: 22159772
Arch Intern Med. 2010 Apr 26;170(8):711-8
pubmed: 20421558
J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):1081-1083
pubmed: 29098794
Health Rep. 2010 Mar;21(1):63-9
pubmed: 20426228
Age Ageing. 2018 Jul 1;47(4):558-564
pubmed: 29546417
Front Endocrinol (Lausanne). 2018 May 25;9:258
pubmed: 29887832
J Am Med Dir Assoc. 2018 Feb;19(2):185.e1-185.e6
pubmed: 29269096
Res Q Exerc Sport. 1999 Jun;70(2):113-9
pubmed: 10380242
J Gerontol. 1994 Mar;49(2):M85-94
pubmed: 8126356
J Am Med Dir Assoc. 2019 May;20(5):634-638.e1
pubmed: 30738823
Neurologia. 2004 Sep;19(7):344-58
pubmed: 15273881
Age Ageing. 2017 May 1;46(3):383-392
pubmed: 28064173
Am J Epidemiol. 2012 Sep 15;176(6):534-43
pubmed: 22935515
Am J Public Health. 2015 Jul;105(7):1439-45
pubmed: 25973826
Gait Posture. 2017 Jan;51:174-180
pubmed: 27780084
Sports Med. 2017 Sep;47(9):1821-1845
pubmed: 28303543
J Cachexia Sarcopenia Muscle. 2020 Apr;11(2):415-423
pubmed: 31912990
BMC Public Health. 2014 Apr 09;14:333
pubmed: 24712381
Med Sci Sports Exerc. 1998 May;30(5):777-81
pubmed: 9588623
PLoS One. 2017 Sep 11;12(9):e0183911
pubmed: 28892505
Science. 2002 May 10;296(5570):1029-31
pubmed: 12004104
J Cachexia Sarcopenia Muscle. 2017 Apr;8(2):213-228
pubmed: 27897402
Med Sci Sports Exerc. 2019 Aug;51(8):1736-1744
pubmed: 30829961
Scand J Med Sci Sports. 2019 Mar;29(3):415-421
pubmed: 30506596
Lancet. 2017 Apr 1;389(10076):1323-1335
pubmed: 28236464
Br J Sports Med. 2019 Sep;53(18):1137-1139
pubmed: 30786998
Exp Gerontol. 2018 Dec;114:1-12
pubmed: 30355522
J Am Geriatr Soc. 1992 Sep;40(9):922-35
pubmed: 1512391
Maturitas. 2015 Feb;80(2):187-91
pubmed: 25542406
J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146-56
pubmed: 11253156
J Am Med Dir Assoc. 2014 May;15(5):371.e7-371.e13
pubmed: 24598478
J Gerontol A Biol Sci Med Sci. 2015 Feb;70(2):163-73
pubmed: 24550352
Nutrients. 2019 Mar 09;11(3):
pubmed: 30857291
Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1089-97
pubmed: 21467238
J Epidemiol Community Health. 2016 Apr;70(4):354-60
pubmed: 26567320
PLoS One. 2012;7(3):e32401
pubmed: 22403651
J Clin Epidemiol. 1997 May;50(5):541-6
pubmed: 9180646
J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1197-204
pubmed: 22459619
Exp Gerontol. 2018 Apr;104:28-34
pubmed: 29421349
J Nutr. 1997 May;127(5 Suppl):990S-991S
pubmed: 9164280
N Engl J Med. 1995 Mar 2;332(9):556-61
pubmed: 7838189