Antiretroviral Treatment Simplification With 2-Drug Regimens: Impact of Transmitted Drug Resistance Mutations.
HIV
dolutegravir
lamivudine
molecular epidemiology
rilpivirine
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
19
11
2019
accepted:
16
12
2019
entrez:
10
1
2020
pubmed:
10
1
2020
medline:
10
1
2020
Statut:
epublish
Résumé
The frequency of clinically relevant transmitted drug resistance mutations (DRMs) against drugs used for 2-drug regimens was 15.6%, but only 2% were not eligible for 1 or more 2-drug regimens. More than 50% of patients harboring any clinically relevant DRMs were found to be part of genetic transmission clusters.
Identifiants
pubmed: 31915716
doi: 10.1093/ofid/ofz535
pii: ofz535
pmc: PMC6942491
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofz535Subventions
Organisme : NIAID NIH HHS
ID : P30 AI036214
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI131971
Pays : United States
Informations de copyright
© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
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