A Regenerative Medicine Approach to the Treatment of Hearing, Balance, and Olfactory Disorders: What Is in the Future for Otolaryngology?


Journal

Anatomical record (Hoboken, N.J. : 2007)
ISSN: 1932-8494
Titre abrégé: Anat Rec (Hoboken)
Pays: United States
ID NLM: 101292775

Informations de publication

Date de publication:
03 2020
Historique:
received: 25 11 2019
accepted: 11 12 2019
pubmed: 10 1 2020
medline: 28 1 2021
entrez: 10 1 2020
Statut: ppublish

Résumé

Regenerative medicine is being applied to many fields of medicine and is now starting to be considered and developed for application to treat hearing, balance, olfaction, and voice disorders. This special issue of the Anatomical Record with a series of over 20 papers covers many aspects of gene and stem cell therapies as they are developed for clinical applications in both in vitro and in vivo laboratory studies. These studies cover a wide range of approaches from gene editing in zebrafish with the latest technology (i.e., CRISPR/Cas9) to the isolation of human inner ear progenitor cells, to tracking transplanted human umbilical cord stem cells in mini pigs, to the in vitro building of graft tissues to repair tracheal defects with adipose tissue-derived stem cells. Anat Rec, 303:385-389, 2020. © 2019 American Association for Anatomy.

Identifiants

pubmed: 31916408
doi: 10.1002/ar.24337
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

385-389

Informations de copyright

© 2019 American Association for Anatomy.

Références

Bas E, Anwar M, Van De Water TR. 2020. TGFB-1 and WNT signaling pathways collaboration associated with cochlear implantation trauma induced fibrosis. Anat Rec.
De Groot S, Sliedregt K, Rivolta M, von Benthem PP, Huisman M. 2020. Building an artificial stem cell niche: prerequisites for future 3D-formation of inner ear structures towards 3D inner ear technology. Anat Rec.
De Smidt A, Zou B, Grati M, Yan D, Mittal R, Yao Q, Richmond M, Denyer S, Liu XZ, Lu Z. 2020. Zebrafish model for nonsyndromic x-linked sensorineural deafness, DFNX-1. Anat Rec.
Dong Y, He X, Wu W, Yang S, Peng A, Xiao Z, Liu Y, Gao S, Peng T, Tan D, et al. 2020. Congenital middle ear malformations with common deafness gene mutational analysis: a review of 813 profound sensorineural hearing loss child patients. Anat Rec.
Eshraghi A, Jung H, Mittal R. 2020. Recent advancements in gene and stem cell based treatment modalities: potential applications in noise induced hearing loss. Anat Rec.
Goncalves S, Goldstein BJ. 2020. Acute N-acetylcysteine ameliorates loss of olfactory neurons following experimental injury in vivo. Anat Rec.
Kada S, Hamaguchi K, Ito J, Omori K, Nakagawa T. 2020. Bone marrow stromal cells accelerate hearing recovery via regeneration or maintenance of cochlear fibrocytes in mouse spiral ligaments. Anat Rec.
Kaiser A, Kale A, Novozilhova E, Olivus P. 2020. The effect of Matrigel of the survival and differentiation of human neural progenitor dissociated sphere culture. Anat Rec.
Kojima K, Nishida A, Tashiro K, Hirota K, Kato N, Nishio T, Murata M, Kawaguchi S, Ito J, Van De Water TR. 2020. Isolation and characterization of mammalian otic stem cells that can differentiate into both sensory and neuronal lineages. Anat Rec.
Kurtenbach S, Goss S, Goncalves S, Choi R, Hare JM, Chaudman N, Goldstein BJ. 2019. Cell-based therapy restores olfactory function in an inducible model of hyposmia. Stem Cell Rep 12(6):1354-1365.
Langston M, Grobman A, Goncalves S, Angeli S. 2020. Animal model of chronic tympanic membrane perforation. Anat Rec.
Matsuoka AJ, Kondo T, Miyamoto RT, Hashino E. 2007. Enhanced survival of bone-marrow-derived pluripotent stem cells in an animal model of auditory neuropathy. Laryngoscope 117(9):1629-1635. https://doi.org/10.1097/MLG.0b013e31806bf282.
Mittal R, Ocak E, Zhu A, Perdomo M, Pena S, Miittal J, Bohorquez J, Eshraghi A. 2020. Effect of bone marrow-derived stem cells on cochlear function in an experimental rat model. Anat Rec.
Nakamura R, Katsuno T, Tateya I, Omori K. 2020. Evaluation of cilia function in rat trachea reconstructed using collagen sponge scaffold seeded with adipose tissue-derived stem cells. Anat Rec.
Pfannensteil S, Praetorius M, Brough D, Straecker H. 2020. Hearing preservation following repeated adenovector delivery. Anat Rec.
Rask-Andersen H, Liu W, Erixon E, Kinnefors A, Pfaller K, Schrott-Fischer A, Glueckert R. 2012. Human cochkea: anatomical characteristics and their relevance for cochlear implantation. Anat Rec 295:1791-1811. https://doi.org/10.1002/ar.22599.
Schomann T, Mezzaneotte L, De Groot J, Lowik C, Frijns J, Huisman M. 2020. Imaging bioluminescent stem cells in the intact Guinea pig cochlea. Anat Rec.
Senn P, Mina A, Volkenstein S, Kranebitter V, Oshima K, Heller S. 2020. Progenitor cells from the human inner ear. Anat Rec.
Usami S, Nishio S, Yoshimura H. 2020. Cochlear implantation from genetic backgrounds view points.
Van De Water TR. 2020. Historical aspects of gene therapy and stem cell therapy in the treatment of hearing and balance disorders. Anat Rec.
Werner M, Van De Water TR, Stenlund H, Berggren D. 2020. Ultrastructural structural characterization of stem cell derived replacement vestibular hair cells within ototoxin-damaged rat utricle explants. Anat Rec.
Xu L, Yuan S, Chen W, Yang S, Guo W, Ma Y, Luo Y. 2020. Transplantation and tracking of the human umbilical cord mesenchymal stem cell labeled with SPIO in deaf pigs. Anat Rec.
Yao Q, Wang L, Mittal R, Yan D, Richmond M, Denyer S, Requena T, Liu K, Varsheny G, Lu Z, et al. 2020. Transcriptomic analyses of sensory epithelia in the inner ear of the zebrafish. Anat Rec.
Zou B, DeSmidt A, Mittal R, Yan D, Richmond M, Tekin M, Liu XZ, Lu Z. 2020. The generation of zebrafish Mariner model using the CRISPR/Cas9 system. Anat Rec.

Auteurs

Thomas R Van De Water (TR)

Cochlear Implant Research Program, Department of Otolaryngology, University of Miami Ear Institute, University of Miami Miller School of Medicine, Miami, Florida.

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