Devastating Gynecological Infections in Women with STAT3 Deficiency.

Cohort Studies Female Humans Mastitis / genetics Mutation Parametritis / genetics STAT3 Transcription Factor / deficiency Young Adult
STAT3 deficiency gynecological infections hyper IgE syndrome mastitis pelvic cellulitis

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
23 10 2020
Historique:
received: 04 09 2019
accepted: 08 01 2020
pubmed: 10 1 2020
medline: 29 4 2021
entrez: 10 1 2020
Statut: ppublish

Résumé

We provide the first description of a series of 9 severe gynecological infections (mastitis and pelvic cellulitis) occurring in the French national cohort of women with STAT3 deficiency. Each episode had unique features in terms of clinical presentation, microbial documentation, location, treatment duration, and related persistent esthetic damage.

Identifiants

DOI: 10.1093/cid/ciaa020 PMID: 31916572
pubmed: 31916572
pii: 5698667
doi: 10.1093/cid/ciaa020
doi:

Substances chimiques

STAT3 Transcription Factor 0
STAT3 protein, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e186-e190

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Auteurs

Alexis Redor (A)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

François Danion (F)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

Perrine Parize (P)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

Olivia Chandesris (O)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

Jonathan Dbjay (J)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

Amélie Duréault (A)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.

Guillaume Le Guenno (G)

Department of Internal Medicine, University Estaing Hospital, Clermont Ferrand, France.

Celine Cazorla (C)

Department of Infectious Diseases and Tropical Medicine, University Hospital, Saint Etienne, France.

Delphine Vergnon-Miszczycha (D)

Department of Infectious Diseases and Tropical Medicine, University Hospital, Saint Etienne, France.

Anne Sophie Bats (AS)

Paris University, Department of Gynecologic Surgery, Georges Pompidou University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

Christine Bodemer (C)

Paris University, Department of Dermatology, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, IHU Imagine, Paris, France.

Cyrille Hoarau (C)

Department of Immunology, University Hospital, Tours, France.

Caroline Charlier (C)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.
French National Reference Center for Primary Immune Deficiencies, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Institut Pasteur, National Reference Center for Invasive Mycoses and Antifungals, Molecular Mycology Unit, Paris, France.

Nizar Mahlaoui (N)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.
French National Reference Center for Primary Immune Deficiencies, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Pediatric Immuno-Hematology and Rheumatology Unit, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

Marc Lecuit (M)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.
French National Reference Center for Primary Immune Deficiencies, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Institut Pasteur, Biology of Infection Unit, Inserm, Paris, France.

Fanny Lanternier (F)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.
French National Reference Center for Primary Immune Deficiencies, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Institut Pasteur, National Reference Center for Invasive Mycoses and Antifungals, Molecular Mycology Unit, Paris, France.

Olivier Lortholary (O)

Paris University, Necker-Pasteur Center for Infectious Diseases and Tropical Medicine, Necker-Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, University Hospital Institute (IHU) Imagine, Paris, France.
French National Reference Center for Primary Immune Deficiencies, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Institut Pasteur, National Reference Center for Invasive Mycoses and Antifungals, Molecular Mycology Unit, Paris, France.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Mastite › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Maladies urogénitales › Maladies génitales › Maladies de l'appareil génital féminin › Maladies des annexes de l'utérus › Maladie inflammatoire pelvienne › Paramétrite › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription STAT › Facteur de transcription STAT-3 › Devastating Gynecological Infections in Women...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Devastating Gynecological Infections in Women...