Perforated and bleeding peptic ulcer: WSES guidelines.
Angiography
Antibiotics
Diagnosis
Embolization
Guidelines
High-risk patients
Intra-abdominal infection
Non-operative management
Pancreatitis
Peptic ulcer
Peritonitis
Surgery
Technique
Timing
Journal
World journal of emergency surgery : WJES
ISSN: 1749-7922
Titre abrégé: World J Emerg Surg
Pays: England
ID NLM: 101266603
Informations de publication
Date de publication:
2020
2020
Historique:
received:
24
10
2019
accepted:
18
12
2019
entrez:
11
1
2020
pubmed:
11
1
2020
medline:
20
3
2021
Statut:
epublish
Résumé
Peptic ulcer disease is common with a lifetime prevalence in the general population of 5-10% and an incidence of 0.1-0.3% per year. Despite a sharp reduction in incidence and rates of hospital admission and mortality over the past 30 years, complications are still encountered in 10-20% of these patients. Peptic ulcer disease remains a significant healthcare problem, which can consume considerable financial resources. Management may involve various subspecialties including surgeons, gastroenterologists, and radiologists. Successful management of patients with complicated peptic ulcer (CPU) involves prompt recognition, resuscitation when required, appropriate antibiotic therapy, and timely surgical/radiological treatment. The present guidelines have been developed according to the GRADE methodology. To create these guidelines, a panel of experts was designed and charged by the board of the WSES to perform a systematic review of the available literature and to provide evidence-based statements with immediate practical application. All the statements were presented and discussed during the 5th WSES Congress, and for each statement, a consensus among the WSES panel of experts was reached. The population considered in these guidelines is adult patients with suspected complicated peptic ulcer disease. These guidelines present evidence-based international consensus statements on the management of complicated peptic ulcer from a collaboration of a panel of experts and are intended to improve the knowledge and the awareness of physicians around the world on this specific topic. We divided our work into the two main topics, bleeding and perforated peptic ulcer, and structured it into six main topics that cover the entire management process of patients with complicated peptic ulcer, from diagnosis at ED arrival to post-discharge antimicrobial therapy, to provide an up-to-date, easy-to-use tool that can help physicians and surgeons during the decision-making process.
Sections du résumé
Background
Peptic ulcer disease is common with a lifetime prevalence in the general population of 5-10% and an incidence of 0.1-0.3% per year. Despite a sharp reduction in incidence and rates of hospital admission and mortality over the past 30 years, complications are still encountered in 10-20% of these patients. Peptic ulcer disease remains a significant healthcare problem, which can consume considerable financial resources. Management may involve various subspecialties including surgeons, gastroenterologists, and radiologists. Successful management of patients with complicated peptic ulcer (CPU) involves prompt recognition, resuscitation when required, appropriate antibiotic therapy, and timely surgical/radiological treatment.
Methods
The present guidelines have been developed according to the GRADE methodology. To create these guidelines, a panel of experts was designed and charged by the board of the WSES to perform a systematic review of the available literature and to provide evidence-based statements with immediate practical application. All the statements were presented and discussed during the 5th WSES Congress, and for each statement, a consensus among the WSES panel of experts was reached.
Conclusions
The population considered in these guidelines is adult patients with suspected complicated peptic ulcer disease. These guidelines present evidence-based international consensus statements on the management of complicated peptic ulcer from a collaboration of a panel of experts and are intended to improve the knowledge and the awareness of physicians around the world on this specific topic. We divided our work into the two main topics, bleeding and perforated peptic ulcer, and structured it into six main topics that cover the entire management process of patients with complicated peptic ulcer, from diagnosis at ED arrival to post-discharge antimicrobial therapy, to provide an up-to-date, easy-to-use tool that can help physicians and surgeons during the decision-making process.
Identifiants
pubmed: 31921329
doi: 10.1186/s13017-019-0283-9
pii: 283
pmc: PMC6947898
doi:
Types de publication
Journal Article
Practice Guideline
Langues
eng
Sous-ensembles de citation
IM
Pagination
3Informations de copyright
© The Author(s). 2020.
Déclaration de conflit d'intérêts
Competing interestsThe authors declare that they have no competing interests.
Références
World J Surg. 2011 Dec;35(12):2650-9
pubmed: 21976010
Surg Endosc. 2016 May;30(5):2026-9
pubmed: 26201415
Clin Imaging. 2004 Sep-Oct;28(5):329-33
pubmed: 15471663
Lancet. 2017 Aug 5;390(10094):613-624
pubmed: 28242110
Endoscopy. 2013;45(3):222-5
pubmed: 23208777
Saudi J Gastroenterol. 2013 Sep-Oct;19(5):195-204
pubmed: 24045592
Gut. 1996 Mar;38(3):316-21
pubmed: 8675081
Aliment Pharmacol Ther. 2011 Aug;34(4):470-5
pubmed: 21707681
Gastrointest Endosc. 2010 Dec;72(6):1138-45
pubmed: 20970794
Gastroenterology. 2017 May;152(6):1310-1318.e1
pubmed: 28167214
J Am Coll Surg. 2004 Mar;198(3):352-5
pubmed: 14992735
Aliment Pharmacol Ther. 2014 Mar;39(5):496-506
pubmed: 24461085
World J Emerg Surg. 2019 Feb 01;14:3
pubmed: 30733822
Lancet. 1997 Oct 4;350(9083):975-9
pubmed: 9329511
Scand J Trauma Resusc Emerg Med. 2013 Apr 10;21:25
pubmed: 23574922
Nat Rev Gastroenterol Hepatol. 2009 Dec;6(12):717-22
pubmed: 19946305
Br J Surg. 2001 Jan;88(1):133-6
pubmed: 11136326
Gastrointest Endosc. 2002 Jul;56(1):1-6
pubmed: 12085028
Clin Exp Gastroenterol. 2014 Apr 16;7:93-104
pubmed: 24790465
World J Gastrointest Surg. 2014 Jan 27;6(1):5-8
pubmed: 24627735
Int J Surg. 2013;11(9):948-51
pubmed: 23806652
J Postgrad Med. 2008 Apr-Jun;54(2):126-34
pubmed: 18480529
Endosc Int Open. 2014 Mar;2(1):E37-40
pubmed: 26134611
JAMA. 2016 Feb 23;315(8):801-10
pubmed: 26903338
World J Gastroenterol. 2012 Oct 28;18(40):5669-78
pubmed: 23155306
Ann Chir. 2004 Dec;129(10):578-82
pubmed: 15581818
BMJ. 2013 Aug 07;347:f4587
pubmed: 23926315
Surg Clin North Am. 2018 Oct;98(5):1047-1057
pubmed: 30243446
World J Surg. 2011 Aug;35(8):1873-8
pubmed: 21533964
Clin Gastroenterol Hepatol. 2009 Jan;7(1):33-47; quiz 1-2
pubmed: 18986845
BMJ. 2008 Apr 26;336(7650):924-6
pubmed: 18436948
Gastrointest Endosc. 2016 Jan;83(1):129-36
pubmed: 26318834
Aliment Pharmacol Ther. 2004 Mar 15;19(6):617-29
pubmed: 15023164
N Engl J Med. 2015 May 21;372(21):1996-2005
pubmed: 25992746
JAMA. 1990 Jul 25;264(4):494-9
pubmed: 2142225
Br J Surg. 2003 Oct;90(10):1215-9
pubmed: 14515289
World J Gastroenterol. 2015 Feb 28;21(8):2497-503
pubmed: 25741160
Gut. 2018 Oct;67(10):1757-1768
pubmed: 29691276
World J Surg. 2014 Aug;38(8):1917-21
pubmed: 24663480
N Engl J Med. 1989 Apr 13;320(15):970-3
pubmed: 2927479
J Laparoendosc Adv Surg Tech A. 2007 Oct;17(5):615-9
pubmed: 17907974
World J Emerg Surg. 2019 Aug 5;14:39
pubmed: 31404221
Ann Chir. 2001 Apr;126(3):232-5
pubmed: 11340708
Am J Med. 2019 Apr;132(4):447-456
pubmed: 30611829
Br J Surg. 2018 Oct;105(11):1487-1492
pubmed: 30024637
Surg Endosc. 2018 Jan;32(1):307-314
pubmed: 28656336
N Engl J Med. 2017 Jun 8;376(23):2235-2244
pubmed: 28528569
Scand J Gastroenterol. 2010 Aug;45(7-8):785-805
pubmed: 20384526
Aliment Pharmacol Ther. 2013 Aug;38(4):329-42
pubmed: 23786250
Aliment Pharmacol Ther. 2011 Mar;33(5):585-91
pubmed: 21205256
Lancet. 2000 Oct 14;356(9238):1318-21
pubmed: 11073021
Langenbecks Arch Surg. 2005 Sep;390(5):413-20
pubmed: 16041553
Surg Endosc. 2013 Sep;27(9):3162-4
pubmed: 23436101
BMC Surg. 2005 Jun 25;5:15
pubmed: 15978134
Eur J Trauma Emerg Surg. 2018 Apr;44(2):251-257
pubmed: 28258286
Arch Surg. 1998 Nov;133(11):1166-71
pubmed: 9820345
Clin Exp Gastroenterol. 2011;4:283-9
pubmed: 22235172
Saudi J Gastroenterol. 2016 Jul-Aug;22(4):309-15
pubmed: 27488326
Surg Laparosc Endosc Percutan Tech. 2014 Apr;24(2):134-9
pubmed: 24686348
South Med J. 2006 May;99(5):467-71
pubmed: 16711308
Diagn Interv Imaging. 2015 Jul-Aug;96(7-8):731-44
pubmed: 26054245
Lancet. 2013 Jun 8;381(9882):2033-43
pubmed: 23746903
Am J Gastroenterol. 2004 Apr;99(4):619-22
pubmed: 15089891
World J Surg. 2017 Apr;41(4):948-953
pubmed: 27882415
N Engl J Med. 1999 Mar 11;340(10):751-6
pubmed: 10072409
Gastrointest Endosc. 2004 Feb;59(2):172-8
pubmed: 14745388
Gastrointest Endosc Clin N Am. 2018 Jul;28(3):307-320
pubmed: 29933777
Clin Gastroenterol Hepatol. 2009 May;7(5):515-23
pubmed: 19418601
Eur Radiol. 2003 Dec;13(12):2604-14
pubmed: 12692680
Am J Gastroenterol. 2006 Mar;101(3):500-5
pubmed: 16542286
BMJ. 2017 Jan 4;356:i6432
pubmed: 28053181
Gastrointest Endosc. 2009 Apr;69(4):786-99
pubmed: 19152905
Clin Exp Gastroenterol. 2016 Oct 31;9:337-343
pubmed: 27826205
J Vasc Interv Radiol. 2009 Apr;20(4):461-6
pubmed: 19328425
Endosc Int Open. 2014 Mar;2(1):E6-E14
pubmed: 26134614
Aliment Pharmacol Ther. 2011 May;33(9):1010-8
pubmed: 21385193
Minerva Anestesiol. 2014 Apr;80(4):470-81
pubmed: 24002461
J Vasc Interv Radiol. 2001 Feb;12(2):195-200
pubmed: 11265883
Cochrane Database Syst Rev. 2013 Jun 12;(6):CD007999
pubmed: 23760821
World J Emerg Surg. 2018 Jan 25;13:6
pubmed: 29416555
Cochrane Database Syst Rev. 2014 Oct 13;(10):CD005584
pubmed: 25308912
Lancet. 2015 Sep 26;386(10000):1288-1298
pubmed: 26460663
Am J Gastroenterol. 2007 Feb;102(2):279-89; quiz 469
pubmed: 17311650
Clin Infect Dis. 2010 Jan 15;50(2):133-64
pubmed: 20034345
Lancet. 2018 Jul 7;392(10141):75-87
pubmed: 29937192
J Gastrointest Surg. 2011 Aug;15(8):1329-35
pubmed: 21567292
J Surg Res. 2017 Dec;220:341-345
pubmed: 29180201
Best Pract Res Clin Gastroenterol. 2013 Oct;27(5):639-47
pubmed: 24160924
Am J Gastroenterol. 2007 May;102(5):1101-7
pubmed: 17355419
Am J Med. 2009 Oct;122(10):896-903
pubmed: 19786155
World J Emerg Surg. 2018 Jun 22;13:26
pubmed: 29977328
Dig Surg. 2010 Aug;27(3):161-9
pubmed: 20571260
Chest. 1996 Sep;110(3):810-5
pubmed: 8797429
Dig Liver Dis. 2015 Nov;47(11):903-12
pubmed: 26253555
World J Emerg Surg. 2014 Aug 03;9:45
pubmed: 25114715
Scand J Gastroenterol. 2016 Oct;51(10):1165-71
pubmed: 27248208
Scand J Trauma Resusc Emerg Med. 2017 Jun 9;25(1):56
pubmed: 28599661
Scand J Gastroenterol. 2014 Jan;49(1):75-83
pubmed: 24256098
Endoscopy. 2014 May;46(5):428-31
pubmed: 24505017
J Gastroenterol. 2016 Mar;51(3):177-94
pubmed: 26879862
Ann Intern Med. 2009 Apr 7;150(7):455-64
pubmed: 19221370
Crit Care. 2019 Mar 27;23(1):98
pubmed: 30917843
J Clin Gastroenterol. 2015 Oct;49(9):738-45
pubmed: 25319738
Gastroenterology. 2007 Jun;132(7):2320-7
pubmed: 17570207
J Clin Diagn Res. 2013 May;7(5):880-2
pubmed: 23814733
Aliment Pharmacol Ther. 2016 Apr;43(7):831-7
pubmed: 26847417
Gastrointest Endosc. 2003 Jan;57(1):62-7
pubmed: 12518133
Ann Surg. 2014 Jun;259(6):1111-8
pubmed: 24368635
World J Gastrointest Surg. 2017 Jan 27;9(1):1-12
pubmed: 28138363
Eur J Trauma Emerg Surg. 2015 Feb;41(1):91-8
pubmed: 25621078
Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005415
pubmed: 17054257
J Trauma Acute Care Surg. 2018 Aug;85(2):417-425
pubmed: 29659470
Eur J Radiol. 2004 Apr;50(1):30-6
pubmed: 15093233
Surg Endosc. 2004 Sep;18(9):1394
pubmed: 15803242
Saudi J Gastroenterol. 2013 Sep-Oct;19(5):205-10
pubmed: 24045593
Endoscopy. 2015 Oct;47(10):a1-46
pubmed: 26417980
Scand J Gastroenterol. 2011 Jul;46(7-8):920-4
pubmed: 21561232
Gastroenterology. 1992 Jan;102(1):139-48
pubmed: 1530782
Clin Microbiol Infect. 2011 Jul;17(7):1061-7
pubmed: 20825438
Indian J Gastroenterol. 2008 May-Jun;27(3):107-9
pubmed: 18787280
Aliment Pharmacol Ther. 2000 Sep;14(9):1119-26
pubmed: 10971227
J Gastrointest Surg. 2014 Jul;18(7):1261-8
pubmed: 24610235
BMJ. 2008 May 10;336(7652):1049-51
pubmed: 18467413
Intensive Care Med. 1996 Jul;22(7):707-10
pubmed: 8844239
Surg Laparosc Endosc Percutan Tech. 2004 Oct;14(5):279-81
pubmed: 15492658
World J Emerg Surg. 2014 Mar 27;9(1):22
pubmed: 24674057
BMJ. 2018 Jun 18;361:k1407
pubmed: 29914871
J Trauma Acute Care Surg. 2013 Sep;75(3):398-403
pubmed: 23928742
Langenbecks Arch Surg. 2009 Jul;394(4):643-6
pubmed: 18418626
J Trauma. 2000 Jun;48(6):991-8; discussion 998-1000
pubmed: 10866242
Clin Microbiol Infect. 2017 Feb;23(2):104-109
pubmed: 27856268
Surg Infect (Larchmt). 2000;1(1):57-63
pubmed: 12594910
Chest. 2017 Mar;151(3):586-596
pubmed: 27876592
Gut. 2012 May;61(5):646-64
pubmed: 22491499
JAMA. 2016 Feb 23;315(8):762-74
pubmed: 26903335
J Gastrointest Surg. 1999 Jan-Feb;3(1):61-5; discussion 66
pubmed: 10457326
World J Emerg Surg. 2016 Jul 15;11:33
pubmed: 27429642
World J Emerg Surg. 2017 Aug 14;12:39
pubmed: 28814969
J Microbiol Immunol Infect. 2017 Jun;50(3):370-376
pubmed: 26321461
Digestion. 2011;84(2):102-13
pubmed: 21494041
Br J Surg. 2014 Jan;101(1):e51-64
pubmed: 24338777
Scand J Gastroenterol. 2017 May;52(5):523-530
pubmed: 28270041
BMC Gastroenterol. 2017 Apr 19;17(1):55
pubmed: 28424073
Br J Surg. 2013 Jul;100(8):1045-9
pubmed: 23754645
World J Emerg Surg. 2018 Apr 6;13:17
pubmed: 29636790
Crit Care Med. 2017 Mar;45(3):486-552
pubmed: 28098591
Gut. 2019 May;68(5):796-803
pubmed: 29802172
N Engl J Med. 2013 Jan 3;368(1):11-21
pubmed: 23281973
Mycopathologia. 2011 Feb;171(2):85-91
pubmed: 20927595
Radiographics. 2007 Jul-Aug;27(4):1055-70
pubmed: 17620467
Scand J Trauma Resusc Emerg Med. 2017 Nov 3;25(1):108
pubmed: 29100549
World J Gastroenterol. 2016 Nov 7;22(41):9162-9171
pubmed: 27895403