Use of triptans during pregnancy? With caution!

Databases, Factual Female Fetal Growth Retardation Humans Pharmacovigilance Pregnancy Tryptamines / adverse effects
Drugs Fetal death Intra-uterine growth retardation Pregnancy Triptans

Journal

Therapie
ISSN: 1958-5578
Titre abrégé: Therapie
Pays: France
ID NLM: 0420544

Informations de publication

Date de publication:
Historique:
received: 18 10 2019
revised: 22 10 2019
accepted: 12 12 2019
pubmed: 12 1 2020
medline: 21 10 2021
entrez: 12 1 2020
Statut: ppublish

Résumé

We report cases, registered in the French national pharmacovigilance database, of fetal death and intrauterine growth retardation in women exposed to triptans during pregnancy. Triptans have vasoconstrictive properties and we wonder about their responsibility for these side effects. The use of triptans and other drugs exhibiting vasoconstrictive properties in pregnant women requires a careful benefits/risks evaluation.

Identifiants

DOI: 10.1016/j.therap.2019.12.007 PMID: 31924306
pubmed: 31924306
pii: S0040-5957(19)30189-1
doi: 10.1016/j.therap.2019.12.007
pii:
doi:

Substances chimiques

Tryptamines 0

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

477-478

Informations de copyright

Copyright © 2019 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

Isabelle Lacroix (I)

Service de pharmacologie médicale et clinique, centre régional de pharmacovigilance, faculté de médecine, Inserm 1027, 31000 Toulouse, France. Electronic address: isabelle.lacroix@univ-tlse3.fr.

Caroline Hurault-Delarue (C)

Service de pharmacologie médicale et clinique, centre régional de pharmacovigilance, faculté de médecine, Inserm 1027, 31000 Toulouse, France.

Delphine Viard (D)

Centre régional de pharmacovigilance, hôpital de Cimiez, 06003 Nice, France.

Bruno Revol (B)

Centre Régional de Pharmacovigilance, CHU Grenoble, Grenoble, France.

Lemya Chaalel (L)

Service de pharmacologie médicale et clinique, centre régional de pharmacovigilance, faculté de médecine, Inserm 1027, 31000 Toulouse, France.

Christine Damase-Michel (C)

Service de pharmacologie médicale et clinique, centre régional de pharmacovigilance, faculté de médecine, Inserm 1027, 31000 Toulouse, France.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Mémorisation et recherche des informations › Bases de données comme sujet › Bases de données factuelles › Use of triptans during pregnancy? With caution!
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles de la croissance › Retard de croissance intra-utérin › Use of triptans during pregnancy? With caution!
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Use of triptans during pregnancy? With caution!
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Pharmacovigilance › Use of triptans during pregnancy? With caution!
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Use of triptans during pregnancy? With caution!
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indoles › Tryptamines › Use of triptans during pregnancy? With caution!