Magnitude and Functional Profile of the Human CD4
Adult
CD4-Positive T-Lymphocytes
/ immunology
CD40 Ligand
/ immunology
Case-Control Studies
Encephalitis Viruses, Tick-Borne
/ immunology
Encephalitis, Tick-Borne
/ blood
Female
Humans
Immunization Schedule
Immunogenicity, Vaccine
Immunologic Memory
Interferon-gamma
/ immunology
Interleukin-2
/ immunology
Male
Middle Aged
Tumor Necrosis Factor-alpha
/ immunology
Up-Regulation
/ immunology
Vaccines, Inactivated
/ administration & dosage
Viral Vaccines
/ administration & dosage
Young Adult
Journal
Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R
Informations de publication
Date de publication:
15 02 2020
15 02 2020
Historique:
received:
13
09
2019
accepted:
10
12
2019
pubmed:
12
1
2020
medline:
22
9
2020
entrez:
12
1
2020
Statut:
ppublish
Résumé
Tick-borne encephalitis (TBE) is a viral infection of the CNS caused by TBE virus. With no specific treatment available, the only protection is a formalin-inactivated whole virus vaccine. Primary immunization with European TBE vaccines, as recommended by the manufacturers, consists of three vaccine doses administered within a 1-y period. Protection from vaccination is believed to be mediated by Abs, yet T cells may also have a protective role. We set out to characterize the human CD4
Identifiants
pubmed: 31924650
pii: jimmunol.1901115
doi: 10.4049/jimmunol.1901115
doi:
Substances chimiques
IFNG protein, human
0
IL2 protein, human
0
Interleukin-2
0
TNF protein, human
0
Tumor Necrosis Factor-alpha
0
Vaccines, Inactivated
0
Viral Vaccines
0
CD40 Ligand
147205-72-9
Interferon-gamma
82115-62-6
Types de publication
Clinical Trial, Phase II
Clinical Trial, Phase III
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
914-922Informations de copyright
Copyright © 2020 by The American Association of Immunologists, Inc.