Knockdown of sodium channel Na
Animals
Cell Proliferation
/ genetics
Dermatitis, Atopic
/ genetics
Down-Regulation
/ genetics
Eosinophils
/ metabolism
Female
Gene Knockdown Techniques
Inflammation
/ genetics
Keratinocytes
/ metabolism
Keratosis
/ genetics
Mast Cells
/ metabolism
Rabbits
Skin
/ cytology
Voltage-Gated Sodium Channels
/ genetics
Journal
Laboratory investigation; a journal of technical methods and pathology
ISSN: 1530-0307
Titre abrégé: Lab Invest
Pays: United States
ID NLM: 0376617
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
28
03
2019
accepted:
22
12
2019
revised:
02
12
2019
pubmed:
12
1
2020
medline:
21
10
2020
entrez:
12
1
2020
Statut:
ppublish
Résumé
The skin plays a critical role in maintenance of water homeostasis. Dysfunction of the skin barrier causes not only delayed wound healing and hypertrophic scarring, but it also contributes to the development of various skin diseases. Dermatitis is a chronic inflammatory skin disorder that has several different subtypes. Skin of contact dermatitis and atopic dermatitis (AD) show epidermal barrier dysfunction. Na
Identifiants
pubmed: 31925326
doi: 10.1038/s41374-020-0371-1
pii: S0023-6837(22)00613-4
doi:
Substances chimiques
Voltage-Gated Sodium Channels
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
751-761Références
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