Comparison of transcutaneous oximetry with symptoms and arteriography in thoracic outlet syndrome.


Journal

Clinical hemorheology and microcirculation
ISSN: 1875-8622
Titre abrégé: Clin Hemorheol Microcirc
Pays: Netherlands
ID NLM: 9709206

Informations de publication

Date de publication:
2020
Historique:
pubmed: 14 1 2020
medline: 15 9 2020
entrez: 14 1 2020
Statut: ppublish

Résumé

Non-invasive tests are still required to improve the holistic diagnostic approach of thoracic outlet syndrome (TOS). We aimed to analyze the diagnostic accuracy of the decrease from rest oxygen pressure (DROP) index of transcutaneous oximetry (TcpO2) in TOS. Seventy-six patients and 40 asymptomatic volunteers (Controls) were enrolled. In TOS-suspected patients, the arteriograms were investigated for the presence of≥75% stenosis. The area under receiver operating characteristics curve (AUC) analysis tested the ability of forearm TcpO2 during provocative maneuvers to discriminate patients from controls and, to predict a positive arteriographic findings in the 44 TOS-suspected patients that had an arteriography. The media [25/75° centile] DROP values of controls and patients were -14 [-8/-22] mmHg and -22 [-12/-42] mmHg, respectively (p for Mann-Whitney<0.02). AUC analysis showed a significant ability of TcpO2 to predict the presence of subclavian arterial compression on arteriography (AUC, 0.694). Although time consuming, tcpO2 is independent of the observer expertise and could be useful in TOS-suspected patients to select the patients that should undergo arteriography.

Sections du résumé

BACKGROUND BACKGROUND
Non-invasive tests are still required to improve the holistic diagnostic approach of thoracic outlet syndrome (TOS).
OBJECTIVES OBJECTIVE
We aimed to analyze the diagnostic accuracy of the decrease from rest oxygen pressure (DROP) index of transcutaneous oximetry (TcpO2) in TOS.
METHODS METHODS
Seventy-six patients and 40 asymptomatic volunteers (Controls) were enrolled. In TOS-suspected patients, the arteriograms were investigated for the presence of≥75% stenosis. The area under receiver operating characteristics curve (AUC) analysis tested the ability of forearm TcpO2 during provocative maneuvers to discriminate patients from controls and, to predict a positive arteriographic findings in the 44 TOS-suspected patients that had an arteriography.
RESULTS RESULTS
The media [25/75° centile] DROP values of controls and patients were -14 [-8/-22] mmHg and -22 [-12/-42] mmHg, respectively (p for Mann-Whitney<0.02). AUC analysis showed a significant ability of TcpO2 to predict the presence of subclavian arterial compression on arteriography (AUC, 0.694).
CONCLUSIONS CONCLUSIONS
Although time consuming, tcpO2 is independent of the observer expertise and could be useful in TOS-suspected patients to select the patients that should undergo arteriography.

Identifiants

pubmed: 31929152
pii: CH190751
doi: 10.3233/CH-190751
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

107-119

Auteurs

Pierre Abraham (P)

Exercise investigation and Sports Medicine, University Hospital, Angers, France.
UMR CNRS 6015, INSERM 1228, Medical School, University of Angers, France.

Jeanne Hersant (J)

Vascular Medicine, University Hospital, Angers, France.

Pierre Ramondou (P)

Vascular Medicine, University Hospital, Angers, France.

Francine Thouveny (F)

Vascular Radiology, University Hospital, Angers, France.

Mathieu Feuilloy (M)

LAUM, UMR CNRS 6613, Groupe ESEO, Angers, France.

Jean Picquet (J)

UMR CNRS 6015, INSERM 1228, Medical School, University of Angers, France.
Thoracic and Vascular Surgery, University Hospital, Angers, France.

Samir Henni (S)

UMR CNRS 6015, INSERM 1228, Medical School, University of Angers, France.
Vascular Radiology, University Hospital, Angers, France.

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