A Novel Technique to Minimize Contamination for Cervical Cancer Surgery Patients.


Journal

Journal of minimally invasive gynecology
ISSN: 1553-4669
Titre abrégé: J Minim Invasive Gynecol
Pays: United States
ID NLM: 101235322

Informations de publication

Date de publication:
Historique:
received: 19 11 2019
revised: 06 01 2020
accepted: 07 01 2020
pubmed: 14 1 2020
medline: 5 2 2021
entrez: 14 1 2020
Statut: ppublish

Résumé

The Laparoscopic Approach to Cervical Cancer (LACC) trial changed the surgical management of cervical cancer worldwide. It was a multinational phase III clinical trial that reported lower survival and higher rate of abdominopelvic recurrences in minimally invasive surgery (MIS) than those of open surgery after hysterectomy. It is possible that tumor exposure to the peritoneal cavity in the MIS arm may account for these differences. We propose a novel technique to minimize peritoneal contamination of malignant cells present at the cervical os by placing a vaginal cerclage abdominally to create a seal at the apex of the vagina during MIS radical hysterectomy. The 2 patients in this work remain healthy and disease-free more than 18 months after surgery using this novel technique. We intend this work to serve as a platform both for offering a safe alternative to the open approach supported by the LACC trial and, most importantly, for promoting discussion of the results of the LACC trial and further research on surgical techniques in the treatment of cervical cancer. MIS has repeatedly been shown to have lower rates of infection, fewer complications, and shorter hospital stays while providing oncologic care that is noninferior to open approach.

Identifiants

pubmed: 31931144
pii: S1553-4650(20)30039-X
doi: 10.1016/j.jmig.2020.01.006
pii:
doi:

Types de publication

Case Reports Journal Article Technical Report Video-Audio Media

Langues

eng

Sous-ensembles de citation

IM

Pagination

1624-1630

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

Auteurs

Martin A Martino (MA)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.. Electronic address: martin_a.martino@lvhn.org.

Kristin Bixel (K)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Andrea M Johnson (AM)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Taylor Wejkszner (T)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Aaron Jacobs (A)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Jose Lazaro (J)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Elizaveta Makarova (E)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

M Bijoy Thomas (MB)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

Jeffrey Fowler (J)

Departments of Gynecologic Oncology (Drs. Martino and Thomas and Ms. Johnson, Ms. Wejkszner, and Ms. Makarova); Plastic Surgery (Dr. Jacobs); Obstetrics and Gynecology (Dr. Lazaro), Lehigh Valley Health Network, Allentown, Pennsylvania; Department of Gynecologic Oncology, Ohio State University (Drs. Bixel and Fowler), Columbus, Ohio.

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