An Experience with Frame-Based Stereotactic Biopsy of Posterior Fossa Lesions via Transcerebellar Route.
Adolescent
Adult
Aged
Brain Diseases
/ pathology
Brain Stem
/ pathology
Case-Control Studies
Cerebellum
/ pathology
Child
Cranial Fossa, Posterior
Equipment Design
Female
Humans
Image-Guided Biopsy
/ instrumentation
Magnetic Resonance Imaging
Male
Middle Aged
Prospective Studies
Stereotaxic Techniques
/ instrumentation
Young Adult
Complication
Magnetic resonance imaging
Oblique
Posterior fossa
Stereotactic biopsy
Transcerebellar
Transfrontal
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
16
08
2019
revised:
31
12
2019
accepted:
02
01
2020
pubmed:
14
1
2020
medline:
9
4
2020
entrez:
14
1
2020
Statut:
ppublish
Résumé
Tissue diagnosis for lesions in the posterior fossa, such as the brainstem, cerebellar peduncle, and cerebellum, is an important determinant of the next treatment option. Herein, we present our 10-year experience with magnetic resonance imaging (MRI)-guided frame-based stereotactic biopsy for 39 patients with posterior fossa lesions, the largest case series in this matter. We performed a retrospective cross-sectional study on all patients with posterior fossa lesion admitted to 2 referral centers between 2006 and 2016. We used Leksell Frame G for stereotactic biopsy of all patients. MRI systems of both hospitals were 1.5 T. We performed analysis on the 39 cases (21 men and 18 women). Age of the patients ranged between 9 and 73 years (mean, 35.4 ± 15.7 years). Localization success rate was 100%. For 38 patients (97.4%), tissue sample size was enough for tissue diagnosis. For 1 case, it was insufficient and nondiagnostic. In this series, we had no surgery-related complications. We present the largest reported series of MRI-guided frame-based stereotactic biopsy of the posterior fossa lesions via a transcerebellar route. We prefer oblique positioning of the frame on the skull and use a transcerebellar route to reduce surgical complications and achieve a greater localization success rate.
Sections du résumé
BACKGROUND
BACKGROUND
Tissue diagnosis for lesions in the posterior fossa, such as the brainstem, cerebellar peduncle, and cerebellum, is an important determinant of the next treatment option. Herein, we present our 10-year experience with magnetic resonance imaging (MRI)-guided frame-based stereotactic biopsy for 39 patients with posterior fossa lesions, the largest case series in this matter.
METHODS
METHODS
We performed a retrospective cross-sectional study on all patients with posterior fossa lesion admitted to 2 referral centers between 2006 and 2016. We used Leksell Frame G for stereotactic biopsy of all patients. MRI systems of both hospitals were 1.5 T.
RESULTS
RESULTS
We performed analysis on the 39 cases (21 men and 18 women). Age of the patients ranged between 9 and 73 years (mean, 35.4 ± 15.7 years). Localization success rate was 100%. For 38 patients (97.4%), tissue sample size was enough for tissue diagnosis. For 1 case, it was insufficient and nondiagnostic. In this series, we had no surgery-related complications.
CONCLUSIONS
CONCLUSIONS
We present the largest reported series of MRI-guided frame-based stereotactic biopsy of the posterior fossa lesions via a transcerebellar route. We prefer oblique positioning of the frame on the skull and use a transcerebellar route to reduce surgical complications and achieve a greater localization success rate.
Identifiants
pubmed: 31931238
pii: S1878-8750(20)30010-3
doi: 10.1016/j.wneu.2020.01.003
pii:
doi:
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e380-e385Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.