The Immunomodulary Effects of Systematic Exercise in Older Adults and People with Parkinson's Disease.

inflammation neurological disorders older people regular training

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
09 Jan 2020
Historique:
received: 18 12 2019
revised: 05 01 2020
accepted: 07 01 2020
entrez: 16 1 2020
pubmed: 16 1 2020
medline: 16 1 2020
Statut: epublish

Résumé

We sought to investigate whether regular balance training of moderate intensity (BT) has an effect on changes in selected cytokines, neurotrophic factors, CD200 and fractalkine in healthy older adults and participants with Parkinson's disease (PD). Sixty-two subjects were divided into groups depending on experimental intervention: (1) group of people with PD participating in BT (PDBT), (2) group of healthy older people participating in BT (HBT), (3,4) control groups including healthy individuals (HNT) and people with PD (PDNT). Blood samples were collected twice: before and after 12 weeks of balance exercise (PDBT, HBT), or 12 weeks apart (PDNT, HNT). The study revealed significant increase of interleukin10 (PDBT,

Identifiants

pubmed: 31936624
pii: jcm9010184
doi: 10.3390/jcm9010184
pmc: PMC7019419
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Narodowe Centrum Nauki
ID : Dec. 2018/02/X/NZ7/01635

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Jadwiga Szymura (J)

Department of Clinical Rehabilitation, Faculty of Motor Rehabilitation, University of Physical Education in Krakow, 31-571 Krakow, Poland.

Jadwiga Kubica (J)

Institute of Physiotherapy, Faculty of Health Science, Jagiellonian University Medical College, 31-126 Krakow, Poland.

Magdalena Wiecek (M)

Department of Physiology and Biochemistry, Faculty of Physical Education and Sport, University of Physical Education in Krakow, 31-571 Krakow, Poland.

Joanna Pera (J)

Department of Neurology, Faculty of Medicine, Jagiellonian University Medical College, 31-503 Krakow, Poland.

Classifications MeSH