Polymer Cancerostatics Containing Cell-Penetrating Peptides: Internalization Efficacy Depends on Peptide Type and Spacer Length.
HPMA copolymers
cancerostatics
cell-penetrating peptides
delivery systems
diagnostics
polymer carriers
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
10 Jan 2020
10 Jan 2020
Historique:
received:
04
12
2019
revised:
30
12
2019
accepted:
07
01
2020
entrez:
16
1
2020
pubmed:
16
1
2020
medline:
16
1
2020
Statut:
epublish
Résumé
Cell-penetrating peptides (CPPs) are commonly used substances enhancing the cellular uptake of various cargoes that do not easily cross the cellular membrane. CPPs can be either covalently bound directly to the cargo or they can be attached to a transporting system such as a polymer carrier together with the cargo. In this work, several CPP-polymer conjugates based on copolymers of
Identifiants
pubmed: 31936737
pii: pharmaceutics12010059
doi: 10.3390/pharmaceutics12010059
pmc: PMC7023232
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Grantová Agentura České Republiky
ID : 17-13283S
Organisme : Grantová Agentura České Republiky
ID : 19-01427S
Organisme : Ministerstvo Zdravotnictví Ceské Republiky
ID : 16-28594A
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : NPU I project POLYMAT (LO1507)
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : Inter-Excellence program, project 39022/2018-1
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