Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.

Animals Basic-Leucine Zipper Transcription Factors / deficiency Cell Differentiation / immunology Chromatin / metabolism Colitis / immunology Disease Models, Animal Epigenesis, Genetic / immunology Forkhead Transcription Factors / metabolism Gastrointestinal Tract / immunology Gene Expression Regulation / immunology Homeostasis / immunology Interferon Regulatory Factors / deficiency Interleukin-10 / biosynthesis Lymphocyte Activation Mice Mice, Inbred C57BL Mice, Mutant Strains Receptors, Antigen, T-Cell / metabolism Signal Transduction / immunology T-Lymphocyte Subsets / immunology T-Lymphocytes, Regulatory / immunology

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
14 01 2020
Historique:
received: 06 09 2019
accepted: 11 12 2019
entrez: 16 1 2020
pubmed: 16 1 2020
medline: 24 4 2020
Statut: epublish

Résumé

Differentiation and homeostasis of Foxp3

Identifiants

DOI: 10.1038/s41467-019-14112-2 PMID: 31937752 PMC: PMC6959360
pubmed: 31937752
doi: 10.1038/s41467-019-14112-2
pii: 10.1038/s41467-019-14112-2
pmc: PMC6959360
doi:

Substances chimiques

Bach2 protein, mouse 0
Basic-Leucine Zipper Transcription Factors 0
Chromatin 0
Forkhead Transcription Factors 0
Foxp3 protein, mouse 0
IL10 protein, mouse 0
Interferon Regulatory Factors 0
Receptors, Antigen, T-Cell 0
interferon regulatory factor-4 0
Interleukin-10 130068-27-8

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

252

Références

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Auteurs

Tom Sidwell (T)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.

Yang Liao (Y)

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3010, Australia.

Alexandra L Garnham (AL)

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3010, Australia.

Ajithkumar Vasanthakumar (A)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
ORCID: 0000-0002-1620-7781

Renee Gloury (R)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.

Jonas Blume (J)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.

Peggy P Teh (PP)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
Renal Medicine, Alfred Health, Melbourne, VIC, 3004, Australia.
Department of Nephrology, Western Health, St Albans, VIC, 3021, Australia.

David Chisanga (D)

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3010, Australia.
ORCID: 0000-0002-0421-3957

Christoph Thelemann (C)

Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.

Fabian de Labastida Rivera (F)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.

Christian R Engwerda (CR)

QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia.
ORCID: 0000-0003-2813-4804

Lynn Corcoran (L)

Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
Department of Medical Biology, The University of Melbourne, Melbourne, VIC, 3010, Australia.

Kohei Kometani (K)

Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan.

Tomohiro Kurosaki (T)

Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan.
Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, 565-0871, Japan.

Gordon K Smyth (GK)

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
School of Mathematics and Statistics, University of Melbourne, Melbourne, VIC, 3010, Australia.
ORCID: 0000-0001-9221-2892

Wei Shi (W)

Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia.
School of Computing and Information Systems, The University of Melbourne, Melbourne, VIC, 3010, Australia.

Axel Kallies (A)

Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, 3010, Australia. axel.kallies@unimelb.edu.au.
Molecular Immunology, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia. axel.kallies@unimelb.edu.au.
ORCID: 0000-0002-6312-6968

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique et à glissière à leucines › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Structures de chromosome › Chromatine › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif hélice ailée › Facteurs de transcription Forkhead › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Système digestif › Tube digestif › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes physiologiques › Homéostasie › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de régulation d'interféron › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-10 › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Attenuation of TCR-induced transcription by...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › Attenuation of TCR-induced transcription by...